anti-Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Antibodies

HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein K Kits (33) and Heterogeneous Nuclear Ribonucleoprotein K Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HNRNPK 3190 P61978
HNRNPK 117282 P61980
HNRNPK 15387 P61979
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Top anti-Heterogeneous Nuclear Ribonucleoprotein K Antibodies at antibodies-online.com

Showing 10 out of 176 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HNRPK Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate Rabbit Anti-HNRPK Antibody  Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: hnRNP K Antibody [NBP1-30975] - Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: hnRNP K Antibody [NBP1-30975] - Paraffin-embedded H1299 xenograft, using antibody at 1:100 dilution. 100 μL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using hnRNP K, antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using hnRNP K, antibody at 1:200 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-HNRPK Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  HepG2 cell lysate Rabbit Anti-HNRPK Antibody  Paraffin Embedded Tissue: Human Skeletal Muscle Cellular Data: Skeletal muscle  Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of hnRNP K (pS284) staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of hnRNP K (pS284) expression in MCF7 EGF-treated (A), Raw264.7 EGF-treated (B), H9C2 EGF-treated (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30', using hnRNP K (Phospho-Ser284) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using HNRNPK antibody (ABIN5970850) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat lung using HNRNPK Antibody (ABIN5970850) at dilution of 1/100 (40x lens). 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from K562/A549/HT-29 cells, using hnRNP K (Ab-284) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, IP, RIP, WB Western blot analysis of extracts of various cell lines, using HNRNPK antibody. 100 μL Log in to see 16 Days
$334.02
Details

Top referenced anti-Heterogeneous Nuclear Ribonucleoprotein K Antibodies

  1. Mouse (Murine) Monoclonal HNRNPK Primary Antibody for ChIP, ELISA - ABIN108575 : Matunis, Michael, Dreyfuss: Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein. in Molecular and cellular biology 1992 (PubMed)
    Show all 3 Pubmed References

  2. Mouse (Murine) Monoclonal HNRNPK Primary Antibody for ChIP, ELISA - ABIN108576 : Blanchette, Fuentes Medel, Gardner: Cell-type-specific and developmental regulation of heterogeneous nuclear ribonucleoprotein K mRNA in the rat nervous system. in Gene expression patterns : GEP 2006 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal HNRNPK Primary Antibody for IF, WB - ABIN516590 : Proepper, Steinestel, Schmeisser, Heinrich, Steinestel, Bockmann, Liebau, Boeckers: Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology. in PLoS ONE 2011 (PubMed)

  4. Chicken Monoclonal HNRNPK Primary Antibody for IHC (p), WB - ABIN2474083 : Bomsztyk, Van Seuningen, Suzuki, Denisenko, Ostrowski: Diverse molecular interactions of the hnRNP K protein. in FEBS letters 1997 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Heterogeneous Nuclear Ribonucleoprotein K Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) interaction partners

  1. hnRNPK regulates PLK1 (show PLK1 Antibodies) expression by competing with the PLK1 (show PLK1 Antibodies)-targeting miRNAs, miR (show MLXIP Antibodies)-149-3p and miR (show MLXIP Antibodies)-193b-5p.

  2. we discovered that hnRNPK plays an important role in bladder cancer, suggesting that it is a potential prognostic marker and a promising target for treating bladder cancer.

  3. The hnRNPK positively regulates the level of prostate tumor overexpressed 1 (show PTOV1 Antibodies)-antisense 1 which harbors five binding sites for miR (show MLXIP Antibodies)-1207-5p. The knockdown of hnRNPK or PTOV1 (show PTOV1 Antibodies)-AS1 (show PTGDR Antibodies) increased the enrichment of heme oxygenase-1 (show HMOX1 Antibodies) mRNA in miR (show MLXIP Antibodies)-1207-5p-mediated miRNA-induced silencing complex and thus suppressed the expression of heme oxygenase-1 (show HMOX1 Antibodies).

  4. High HNRNPK expression is associated with pancreatic cancer.

  5. Down-regulation of DAB2IP (show DAB2IP Antibodies) correlated negatively with hnRNPK and MMP2 (show MMP2 Antibodies) expressions in CRC (show CALR Antibodies) tissues. In conclusion, our study elucidates a novel mechanism of the DAB2IP (show DAB2IP Antibodies)/hnRNPK/MMP2 (show MMP2 Antibodies) axis in the regulation of CRC (show CALR Antibodies) invasion and metastasis, which may be a potential therapeutic target.

  6. Tumor cells bearing a p53 (show TP53 Antibodies) mutation showed increased damage levels and delayed repair. Knockdown of hnRNPK applied simultaneously with irradiation reduced colony-forming ability and survival of tumor cells. Taken together, our data shows that hnRNPK is a relevant modifier of DNA damage repair and tumor cell survival. We therefore recommend further studies to evaluate the potential of hnRNPK as a drug target for improvement

  7. Data suggest that hnRNPK plays role in heat shock response of cells by regulating HSF1; hnRNPK inhibits HSF1 activity, resulting in reduced expression of HSP27 and HSP70 mRNAs; hnRNPK also down-regulates binding of HSF1 to heat shock response element. (hnRNPK = heterogeneous-nuclear ribonucleoprotein K; HSF1 = heat shock transcription factor 1; HSP = heat-shock protein)

  8. KRAS-mutant colorectal carcinoma shows intrinsic radioresistance along with rapid upregulation of hnRNP K in response to ionizing radiation that can effectively be targeted by MEK (show MAP2K1 Antibodies) inhibition.

  9. Nujiangexathone A, a novel compound from Garcinia nujiangensis, down-regulates hnRNPK levels in cervical tumor cells, inducing cell cycle arrest.

  10. Our study also suggests that loss of function variants in HNRNPK should be considered as a molecular basis for patients with Kabuki-like syndrome

Xenopus laevis Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) interaction partners

  1. A novel role for the nuclear localization signal in regulating hnRNP K protein stability in vivo has been described.

  2. a previously unidentified function of phosphorylation at this phylogenetically conserved site and implicates hnRNPK as an intracellular molecular target of ERK (show MAPK1 Antibodies)-mediated signaling in axon outgrowth.

  3. hnRNP K is essential for successful optic axon regeneration via a novel post-transcriptional regulatory pathway.

  4. A crucial role is reported for hnrpk in axon development in Xenoops laevis.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) interaction partners

  1. This is the first study revealing the presence of a parallel increase in expressions of FTO (show FTO Antibodies) and HNRNPK proteins. This increase may codictate the metabolic changes occurring in the cell and may attribute a significance to HNRNPK in FTO (show FTO Antibodies)-associated transformations.

  2. hnRNPK recruits PCGF3 (show PCGF3 Antibodies)/5-PRC1 (show PRC1 Antibodies) to the Xist RNA B-repeat to establish polycomb (show CBX2 Antibodies)-mediated chromosomal silencing.

  3. the beneficial actions of insulin (show INS Antibodies) in diabetic nephropathy appear to be mediated, in part, by suppressing renal Nrf2 (show NFE2L2 Antibodies) and Agt (show AGXT Antibodies) gene transcription and preventing Nrf2 (show NFE2L2 Antibodies) stimulation of Agt (show AGXT Antibodies) expression via hnRNP F (show HNRNPF Antibodies)/K.

  4. the cytoplasmic hnRNPK interacts with GSK3beta and regulates its function.

  5. Data implicate hnRNPK in the development of hematological disorders and suggest hnRNPK acts as a tumor suppressor.

  6. These findings functionally integrate K17 (show KRT17 Antibodies), hnRNP K, and gene expression along with RSK (show RPS6KA1 Antibodies) and CXCR3 (show CXCR3 Antibodies) signaling in a keratinocyte-autonomous axis and provide a potential basis for their implication in tumorigenesis

  7. Nova haploinsufficient mice had spontaneous epilepsy

  8. HnRNP K-3' UTR (show UTS2R Antibodies) complex inhibits TAK1 (show NR2C2 Antibodies) mRNA translation.

  9. hnRNP-K regulates extracellular matrix, cell motility, and angiogenesis pathways. Involvement of the selected genes (Cck (show CCK Antibodies), Mmp-3 (show MMP3 Antibodies), Ptgs2 (show PTGS2 Antibodies), and Ctgf (show CTGF Antibodies)) and pathways was validated by gene-specific expression analysis

  10. HNRNPK affects production of the essential NEAT1_2 isoform by negatively regulating its 3'-end polyadenylation by arresting CFIm (show CPSF6 Antibodies) complex binding near NEAT1_1's alternative polyadenylation site.

Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) Antigen Profile

Protein Summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference\; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Gene names and symbols associated with HNRNPK

  • heterogeneous nuclear ribonucleoprotein K (HNRNPK) antibody
  • heterogeneous nuclear ribonucleoprotein K (Hnrnpk) antibody
  • heterogeneous nuclear ribonucleoprotein K S homeolog (hnrnpk.S) antibody
  • heterogeneous nuclear ribonucleoprotein K (hnrnpk) antibody
  • heterogeneous nuclear ribonucleoprotein K (LOC5565718) antibody
  • heterogeneous nuclear ribonucleoprotein k (CpipJ_CPIJ000130) antibody
  • heterogeneous nuclear ribonucleoprotein K (NGK_p0004) antibody
  • Csbp antibody
  • hnrpk antibody
  • KBBP antibody
  • MGC75642 antibody
  • NOVA antibody
  • TUNP antibody
  • wu:fb37h02 antibody
  • wu:fi34c04 antibody
  • zgc:66162 antibody

Protein level used designations for HNRNPK

dC-stretch binding protein , transformation upregulated nuclear protein , dC stretch-binding protein , hnRNP K , heterogeneous nuclear ribonucleoprotein K , heterogeneous nuclear ribonucleoprotein k , hnRNP-K protein , heterogeneous nuclear ribonucleoprotein K-like

GENE ID SPECIES
3190 Homo sapiens
117282 Rattus norvegicus
380255 Xenopus laevis
394952 Xenopus (Silurana) tropicalis
406267 Danio rerio
464554 Pan troglodytes
528135 Bos taurus
5565718 Aedes aegypti
6030937 Culex quinquefasciatus
6446928 Neisseria gonorrhoeae NCCP11945
100008849 Oryctolagus cuniculus
100173769 Pongo abelii
15387 Mus musculus
427458 Gallus gallus
100052735 Equus caballus
100390554 Callithrix jacchus
100601168 Nomascus leucogenys
100855638 Canis lupus familiaris
100861302 Capra hircus
101117560 Ovis aries
100622191 Sus scrofa
100729110 Cavia porcellus
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