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The protein encoded by FIL1h is a member of the interleukin 1 cytokine family. Additionally we are shipping and and many more products for this protein.
Showing 10 out of 40 products:
Human FIL1h ELISA Kit for Sandwich ELISA - ABIN418831
Kur?unlu, Oztürk, Han, Atmaca, Emingil: Gingival crevicular fluid interleukin-36? (-1F8), interleukin-36? (-1F9) and interleukin-33 (-1F11) levels in different periodontal disease. in Archives of oral biology 2014
IL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skin
Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
A critical role of IL-36R ligands in the interface between innate and adaptive immunity, leading to the stimulation of T helper responses.
The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce any of the classical IL-1 responses in glial cells.
IL-36-mediated IL-6 and CXCL8 production in human lung fibroblasts and bronchial epithelial cells may be involved in pulmonary inflammation especially caused by bacterial or viral infections.
With a focus on the skin as a target for microbial and viral invasion, the current knowledge of IL-36: IL-36alpha, IL-36beta and IL-36gamma, functions is reviewed. One physiological function of the IL-36smay be to counteract microbial immune evasion. [Review]
IL36B expression is induced in keratinocytes by Toll-like receptor ligands suggesting a function in barrier immune defense.
IL-1F8 functions as an inducer of antimicrobial peptide and matrix metalloproteinase expression by keratinocytes; IL-1F8 is overexpressed in transgenic psoriatic model mouse skin.
IL-1F6 and IL-1F8, in addition to IL-1F9, activate the pathway leading to NF-kappaB in an IL-1Rrp2-dependent manner in Jurkat cells
Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in samples from patients with rheumatoid arthritis
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
, interleukin-1 family member 8
, interleukin-36 beta
, FIL1 eta
, IL-1 eta
, IL-1F8 (FIL1-eta)
, IL1F8 (Canonical product IL-1F8a)
, Interleukin-1 Superfamily e
, family of interleukin 1-eta
, interleukin 1 family, member 8 (eta)
, interleukin 1, eta
, interleukin-1 eta
, interleukin-1 homolog 2
, interleukin 1 family, member 8