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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. Additionally we are shipping Killer Cell Lectin-Like Receptor Subfamily C, Member 3 Antibodies (13) and many more products for this protein.
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expression of CD94 (show KLRD1 Proteins) and its associated NKG2A (show KLRC1 Proteins), NKG2C (show KLRC2 Proteins), and NKG2E subunits is dispensable for NK cell development, education, and many NK cell functions
KLRC3 gene expression is linked to glioblastoma aggressiveness.
Data indicate that NKG2 receptor NKG2E was capable of associating with CD94 (show KLRD1 Proteins) and DAP12 (show TYROBP Proteins) but that the complex was retained intracellularly at the endoplasmic reticulum.
Data indicate that the expression of KLRD1 (CD94 (show KLRD1 Proteins)) and NKG2E (KLRC3) was reduced in NK-enriched cells in fulminant type 1 diabetes.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
killer cell lectin-like receptor subfamily C, member 2
, natural killer cell group 2E cell receptor
, killer cell lectin-like receptor subfamily C, member 3
, NKG2-E type II integral membrane protein
, NK cell receptor E
, NKG2-E-activating NK receptor