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Laminin gamma 1 Proteins

(Laminin, gamma 1 (LAMC1))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis. [provided by RefSeq, Aug 2011].
Laminin gamma 1 Protein (AA 1-38) (GST tag) Laminin gamma 1 Protein (AA 1-38) (GST tag) Laminin gamma 1 Protein (AA 1-38) (GST tag) (ABIN1309130)

LAMC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

Laminin gamma 1 Protein (AA 34-1609) (His tag) Laminin gamma 1 Protein (AA 34-1609) (His tag) Laminin gamma 1 Protein (AA 34-1609) (His tag) (ABIN3093542)

Crystallography grade LAMC1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Laminin gamma 1 Protein (AA 34-1607) (His tag) Laminin gamma 1 Protein (AA 34-1607) (His tag) Laminin gamma 1 Protein (AA 34-1607) (His tag) (ABIN3132431)

Crystallography grade LAMC1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Laminin gamma 1 Proteins by Grade

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Laminin gamma 1 Proteins by Origin

Find Laminin gamma 1 Proteins for a variety of species such as anti-Human Laminin gamma 1, anti-Mouse Laminin gamma 1, anti-Rat Laminin gamma 1. The species listed below are among those available. Click on a link to go to the corresponding products.

Laminin gamma 1 Proteins by Source

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Laminin gamma 1 Proteins by Protein Type

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Laminin gamma 1 Proteins by Application

Find Laminin gamma 1 Proteins validated for a specific application such as WB, SDS, ELISA, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Laminin gamma 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309130
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093542
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3132431
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395857
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402949
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403222
Quantity 100 μg
Datasheet Datasheet
Reactivity CHO cells
Source Insect Cells
Validations
Cat. No. ABIN7126008
Quantity 0.5 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3010418
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3010419
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724492
Quantity 20 μg
Datasheet Datasheet

Aliases for Laminin gamma 1 Proteins

putative laminin gamma-1 chain (Smp_163810) Proteins
laminin subunit gamma 1 (lamc1) Proteins
laminin, gamma 1 (Lamc1) Proteins
laminin subunit gamma 1 (Lamc1) Proteins
laminin, gamma 1 (lamc1) Proteins
laminin subunit gamma 1 (LAMC1) Proteins
B2e Proteins
lamb2 Proteins
Lamb2 Proteins
LAMB2 Proteins
sly Proteins
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