anti-MyoD Family Inhibitor Domain Containing (MDFIC) Antibodies

MDFIC product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Additionally we are shipping MDFIC Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MDFIC 29969 Q9P1T7
MDFIC 16543 Q8BX65
MDFIC 362325  
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Top anti-MDFIC Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MDFIC Antibody Titration:  0.2-1 ug/ml  Positive Control:  MCF7 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-MDFIC Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of MDFIC Antibody (N-term) (ABIN652654) in Hela cell line lysates (35 µg/lane). MDFIC (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human spleen reacted with MDFIC Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of MDFIC Antibody (N-term) in Hela cell line lysates (35ug/lane). MDFIC (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL 11 to 13 Days
$335.04
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunofluorescent staining of human cell line A-431 with MDFIC polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and golgi apparatus. Immunohistochemical staining of human duodenum with MDFIC polyclonal antibody  strong cytoplasmic positivity in glandular cells. 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated WB MDFIC antibody used at 0.2-1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details

More Antibodies against MDFIC Interaction Partners

Human MyoD Family Inhibitor Domain Containing (MDFIC) interaction partners

  1. GR directly represses the MDFIC gene, revealing a negative feedback loop by which glucocorticoids limit MDFIC activity. These findings identify a new binding partner for cytoplasmic GR that modulates the receptor transcriptome and contributes to the tissue-specific actions of glucocorticoids.

  2. HIC specifically interacts with HTLV-1 Tax and negatively regulates Tax transactivational activity by altering its subcellular distribution and stability.

  3. We demonstrate that HIC selectively interferes with Rev NLS interaction with importin beta and impedes its nuclear import and function, but does not affect Rev nuclear import mediated by transportin.

  4. These data reveal for the first time that I-mfa domain proteins interact with LANA and negatively regulate LANA-mediated activation of Wnt signaling-dependent transcription by inhibiting the formation of the LANA.GSK-3beta complex.

  5. This study describes that the immune expression of HIC is cell-specific, dynamic, and identifies the HIC gene as an IL-2 responsive gene.

  6. strict regulation of HIC expression at the levels of mRNA stability, translation efficiency and protein stability suggests that expression of the HIC protein and its involvement in the various pathways is required only under specific cellular conditions

  7. Two isoforms, resulting from the use of a non-AUG (GUG) and a downstream in-frame AUG translation initiation codon, have different subcellular localization.

Xenopus laevis MyoD Family Inhibitor Domain Containing (MDFIC) interaction partners

  1. Data indicate a role for XIC in limiting Tcf3-dependent repression of Siamois activities that are required for goosecoid transcription and for dorsal organizer formation.

MDFIC Antigen Profile

Protein Summary

This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization\; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MDFIC

  • MyoD family inhibitor domain containing (MDFIC) antibody
  • MyoD family inhibitor domain containing (Mdfic) antibody
  • MyoD family inhibitor domain containing S homeolog (mdfic.S) antibody
  • HIC antibody
  • Kdt1 antibody
  • Mdfid antibody

Protein level used designations for MDFIC

MyoD family inhibitor domain containing , myoD family inhibitor domain-containing protein , myoD family inhibitor domain-containing , I-mfa domain-containing protein , MyoD family inhibitor domain containing protein , kidney cell line-derived transcript 1 , kidney cell line derived transcript 1 , I-mfa domain protein XIC , XIC

GENE ID SPECIES
417774 Gallus gallus
735818 Pan troglodytes
100137388 Papio anubis
100422733 Ailuropoda melanoleuca
29969 Homo sapiens
100328794 Oryctolagus cuniculus
100192442 Sus scrofa
520530 Bos taurus
16543 Mus musculus
612042 Canis lupus familiaris
362325 Rattus norvegicus
398213 Xenopus laevis
Selected quality suppliers for anti-MDFIC (MDFIC) Antibodies
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