N-Myc Downstream Regulated 1 (NDRG1) ELISA Kits

NDRG1 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Additionally we are shipping N-Myc Downstream Regulated 1 Antibodies (174) and N-Myc Downstream Regulated 1 Proteins (16) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NDRG1 10397 Q92597
NDRG1 17988 Q62433
NDRG1 299923 Q6JE36
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Top N-Myc Downstream Regulated 1 ELISA Kits at antibodies-online.com

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Human 7 pg/mL 28-1800 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
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Human 0.21 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 2 to 3 Days
$867.90
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Rat
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$875.60
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Cow
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More ELISA Kits for N-Myc Downstream Regulated 1 Interaction Partners

Human N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. we demonstrated that the novel molecule of cell migration and invasion, caveolin-1, has direct interaction with NDRG1 in human colorectal cancer cells

  2. strong NDRG1 expression in ciliated epithelial cells in nasal tissues sampled from patients with chronic rhinosinusitis. NDRG1 gene knockdown decreased the transepithelial electrical resistance and increased the dextran permeability. NDRG1 knockdown disrupted tight junctions of airway epithelial cells. NDRG1 knockdown significantly decreased only claudin-9 (show CLDN9 ELISA Kits) expression, but did not decrease other claudin family molecules.

  3. Study elucidates a mechanism of NDRG1-regulated Wnt (show WNT2 ELISA Kits) pathway activation and EMT (show ITK ELISA Kits) via affecting TLE2 (show TLE2 ELISA Kits) and beta-catenin (show CTNNB1 ELISA Kits) expression in esophageal cancer cells.

  4. NDRG1 prevented the degradation of c-Myc (show MYC ELISA Kits) through Skp2-mediated ubiquitination in tumor cells. NDRG1 directly interacted with Skp2, and decreased phosphorylation of Skp2 through inactivation of CDK2 (show CDK2 ELISA Kits).

  5. Data suggest that NDRG1 attenuates oncogenic signaling by inhibiting formation of EGFR (show EGFR ELISA Kits)/HER2 (show ERBB2 ELISA Kits) and HER2 (show ERBB2 ELISA Kits)/HER3 (show ERBB3 ELISA Kits) heterodimers and by down-regulating EGFR (show EGFR ELISA Kits) via a mechanism involving its degradation. (NDRG1 = N-myc downstream regulated gene 1 protein; EGFR (show EGFR ELISA Kits) = epidermal growth factor receptor (show EGFR ELISA Kits); HER = human epidermal growth factor receptor (show EGFR ELISA Kits)) [REVIEW]

  6. NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors

  7. NDRG1 overexpression leads to reduced tumor growth and angiogenesis in experimental glioma via upregulation of TNFSF15. In NDRG1 overexpressing glioma antiangiogenic treatment does not yield a therapeutic response.

  8. The current study is the first to elucidate a unique facet of the potent tumor/metastasis suppressor NDRG1 in the regulation of pancreatic ductal adenocarcinoma (PDAC)glycolysis, leading to important insights into the mechanism by which NDRG1 exert inhibitory function in PDAC.

  9. The mean nerve NDRG1 expression score was 5.4.

  10. Hereditary motor and sensory neuropathy-type Lom in 12 Czech patients, carrying NDRG1 mutation and one unusual case due to uniparental isodisomy of chromosome 8 has been reported.

Mouse (Murine) N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors

  2. NDR1 (show STK38 ELISA Kits) kinase, activated by the Rap1 (show TERF2IP ELISA Kits) signaling cascade through RAPL (show RASSF5 ELISA Kits) and Mst1 (show MST1 ELISA Kits)/Mst2 (show STK3 ELISA Kits), associated with and recruited kindlin-3 (show FERMT3 ELISA Kits) to the immunological synapses, which was required for high-affinity LFA-1 (show ITGAL ELISA Kits)/ICAM-1 (show ICAM1 ELISA Kits) binding.

  3. Snell, GHKRO, and PAPPA (show PAPPA ELISA Kits)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (show MGMT ELISA Kits)) and N-myc downstream-regulated gene 1 (NDRG1).

  4. NDRG1 deficiency attenuates the differentiation of macrophage lineage cells, suppressing bone remodeling and inflammatory angiogenesis. This study strongly suggests the crucial role of NDRG1 in differentiation process for macrophages.

  5. Using double knockout of NDR1 (show STK38 ELISA Kits) and 2 shows that NDRs acted downstream of MST1 (show MST1 ELISA Kits) to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.

  6. Ndrg1 is phosphorylated and degraded by CD28 (show CD28 ELISA Kits) signalling in a proteasome-dependent manner.

  7. Ndr1 (show STK38 ELISA Kits)/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR (show STK38 ELISA Kits) kinases are critically required during the early phase of organogenesis

  8. Rassf5 (show RASSF5 ELISA Kits) and Ndr1 (show STK38 ELISA Kits) or Ndr2 kinases regulate neuronal polarity through Par3 (show F2RL2 ELISA Kits) phosphorylation.

  9. NDRG1 promotes fetal growth and regulates the metabolic response to intrauterine hypoxic injury in a sexually dichotomous manner

  10. early growth response 1 (show EGR1 ELISA Kits), a transcription factor that binds to the NDRG1 promoter, was mediated in the NDRG1 expression regulation by PKD2 (show PKD2 ELISA Kits).

Arabidopsis thaliana N-Myc Downstream Regulated 1 (NDRG1) interaction partners

  1. NDR1 plays a broad role both in mediating primary cellular functions in Arabidopsis through maintaining the integrity of the cell wall-plasma membrane connection and as a key signaling component of these responses during pathogen infection.

  2. SR1 plays an important role in plant immunity and ethylene signaling by directly regulating NDR1 and EIN3.

  3. The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.

  4. Sequence analysis and mass spectrometry suggest that NDR1 (show STK38 ELISA Kits) is localized to the PM via a C-terminal glycosylphosphatidyl-inositol (GPI (show GPI ELISA Kits)) anchor.

  5. demonstrate that the RIN4-NDR1 interaction occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is required for the activation of resistance signaling following infection by P. syringae

  6. Mutations in NDR1 (show STK38 ELISA Kits) abolished the enhanced resistance of dnd (show DND1 ELISA Kits) mutants against Pseudomonas syringae pv. tomato and Hyaloperonospora parasitica but not Botrytis cinerea.

N-Myc Downstream Regulated 1 (NDRG1) Antigen Profile

Antigen Summary

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NDRG1

  • N-myc downstream regulated 1 (NDRG1) antibody
  • N-myc downstream regulated gene 1 (Ndrg1) antibody
  • N-myc downstream regulated 1 (Ndrg1) antibody
  • N-myc downstream regulated 1 S homeolog (ndrg1.S) antibody
  • N-myc downstream regulated 1 (ndrg1) antibody
  • N-myc downstream regulated 1a (ndrg1a) antibody
  • Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family (NDR1) antibody
  • cap43 antibody
  • cb775 antibody
  • cmt4d antibody
  • DRG-1 antibody
  • drg1 antibody
  • gc4 antibody
  • hmsnl antibody
  • ndr1 antibody
  • NDRG1 antibody
  • ndrg4 antibody
  • Ndrl antibody
  • nmsl antibody
  • NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN antibody
  • non race-specific disease resistance 1 antibody
  • proxy1 antibody
  • rit42 antibody
  • rtp antibody
  • targ1 antibody
  • tdd5 antibody
  • wu:fb60h02 antibody
  • xndrg1 antibody
  • zgc:63944 antibody

Protein level used designations for NDRG1

N-myc downstream-regulated gene 1 protein , differentiation-related gene 1 protein , nickel-specific induction protein Cap43 , protein NDRG1 , protein regulated by oxygen-1 , reducing agents and tunicamycin-responsive protein , N-myc downstream regulated 1 , protein Ndr1 , N-myc downstream regulated gene 1 , protein NDRG1-B , xNDRG1-B , protein NDRG1-like

GENE ID SPECIES
10397 Homo sapiens
17988 Mus musculus
299923 Rattus norvegicus
380319 Xenopus laevis
420321 Gallus gallus
464411 Pan troglodytes
482049 Canis lupus familiaris
493508 Xenopus (Silurana) tropicalis
504499 Bos taurus
792085 Danio rerio
100068997 Equus caballus
100230327 Taeniopygia guttata
100401077 Callithrix jacchus
100466806 Ailuropoda melanoleuca
100596235 Nomascus leucogenys
697752 Macaca mulatta
821607 Arabidopsis thaliana
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