Neuroglobin Proteins (NGB)

NGB encodes an oxygen-binding protein that is distantly related to members of the globin gene family. Additionally we are shipping Neuroglobin Antibodies (95) and Neuroglobin Kits (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NGB 58157 Q9NPG2
NGB 64242 Q9ER97
NGB 85382 Q99JA8
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Top Neuroglobin Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,465.26
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Log in to see 11 Days
$411.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Rabbit His tag   1 mg Log in to see 60 to 71 Days
$2,333.83
Details
Yeast Wild boar His tag   1 mg Log in to see 60 to 71 Days
$2,333.83
Details
Yeast Dog His tag   1 mg Log in to see 60 to 71 Days
$2,333.83
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,333.83
Details
Yeast Rhesus Monkey His tag   1 mg Log in to see 60 to 71 Days
$2,333.83
Details

NGB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , , ,
Mouse (Murine)
,
Rat (Rattus) ,

Top referenced Neuroglobin Proteins

  1. Human Neuroglobin Protein expressed in Wheat germ - ABIN1312525 : Powers: p53-mediated apoptosis, neuroglobin overexpression, and globin deposits in a patient with hereditary ferritinopathy. in Journal of neuropathology and experimental neurology 2006 (PubMed)

More Proteins for Neuroglobin (NGB) Interaction Partners

Human Neuroglobin (NGB) interaction partners

  1. Results show that the expression of NGB (show GTPBP4 Proteins) in glioma is grade related and is negatively regulated at the transcriptional level by PPARgamma (show PPARG Proteins) suggesting an important role of NGB (show GTPBP4 Proteins) in glioma progression.

  2. The authors demonstrate that Glu53, Glu60, and Glu118 of human Ngb (show GTPBP4 Proteins) are crucial for both the neuroprotective activity and interaction with Gi. Moreover, they show that Lys46, Lys70, Arg208, Lys209, and Lys210 residues of Gi are important for binding to human Ngb (show GTPBP4 Proteins).

  3. Ngb-H64Q-CCC binds CO about 500 times more strongly than hemoglobin, which could be useful in detecting and eliminating carbon monoxide poisoning

  4. these results highlight the involvement of ERa activation and of E2/ERa-dependent NGB (show GTPBP4 Proteins) upregulation in the insensitivity of MCF-7 to paclitaxel. These novel findings could have important implications in the development of targeted therapeutics for overcoming paclitaxel insensitivity in ERa-positive human breast cancer

  5. Knockdown of GATA-2 (show GATA2 Proteins) caused NGB (show GTPBP4 Proteins) expression to drop dramatically, indicating GATA-2 (show GATA2 Proteins) as an essential transcription factor for the activation of NGB (show GTPBP4 Proteins) expression via binding to a novel distal regulatory element of NGB (show GTPBP4 Proteins).

  6. analysis of how the interaction of hydrogen sulfide (show SQRDL Proteins) with human neuroglobin is muted (show MUTED Proteins) by a distal ligand

  7. NO oxidation kinetics at physiological NO concentrations. The use of a polarized electrode to efficiently interconvert the ferric (Fe(3+)) and ferrous (Fe(2+)) forms of an immobilized NGB (show GTPBP4 Proteins) showed that the disulfide bridge both defines the kinetics of NO dioxygenase activity and regulates appearance of the free ferrous deoxy-NGB (show GTPBP4 Proteins), which is the redox active form of the protein in contrast to oxy (show GCG Proteins)-NGB (show GTPBP4 Proteins).

  8. Taken together, this work support the first evidence that Ngb (show GTPBP4 Proteins) can be potentially used as a promising biomarker and target for novel treatment of human glioma

  9. The (show GTPBP4 Proteins) cochlear nuclei and superior olivary complex (SOC) also express considerable amounts of Ngb. Within the human SOC, many medial superior olive neurons, and scattered neurons in the LSO, were Ngb-immunoreactive

  10. Study characterized the presence of Ngb (show GTPBP4 Proteins) in the human cochlea

Mouse (Murine) Neuroglobin (NGB) interaction partners

  1. This is the first report demonstrating a similar pattern of Ngb expression during disease progression in the brains of R6/2 mice.

  2. NGB proved to act cytoprotectively during MI in the acute setting while this effect was less pronounced in the atherosclerosis model.

  3. Study showed that in Neuroglobin (Ngb) knockout mice, distortion-product otoacoustic emissions thresholds were moderately augmented in the range of 5-18kHz. Results suggest that the lack of NgB, results in only marginal deficits in hearing ability.

  4. Ngb-H64Q-CCC binds CO about 500 times more strongly than hemoglobin, which could be useful in detecting and eliminating carbon monoxide poisoning

  5. Ngb can bind to mitochondrial complex III subunit Cyc1 (show CYC1 Proteins), leading to suppression of oxygen-glucose deprivation -mediated complex III activity.

  6. Reduction of Ngb expression in mouse retina after optic nerve injury.Ngb role in neuroregeneration in mice after optic nerve injury.

  7. Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF (show REST Proteins) being an upstream regulator.

  8. Ngb expression is limited to the subpopulation of type I spiral ganglion cells, those which innervate inner hair cells, while the subpopulation of type II spiral ganglion cells which innervate the outer hair cells do not express Ngb. The cochlear nuclei and superior olivary complex (SOC (show UBXN11 Proteins)) also express considerable amounts of Ngb.

  9. Ngb functions as a metabolic regulator and enhances cellular anabolism through the inhibition of AMPK (show PRKAA1 Proteins) signaling.

  10. Data show that the neuroglobin (Ngb) protein was downregulated in the retinal ganglion cells after optic nerve injury.

Pig (Porcine) Neuroglobin (NGB) interaction partners

  1. Constitutive expression levels of neuroglobin in neonatal brain cells may explain mild neuronal injury after 60 min. of deep hypothermic circulatory arrest.

Zebrafish Neuroglobin (NGB) interaction partners

  1. The zebrafish Neuroglobin can catalyze the reduction of nitrite to nitric oxide with a broad range of reaction rate constants.

  2. Data show that the neuroglobin (Ngb) protein was upregulated in the amacrine cells after optic nerve injury.

  3. Chimeric Myoglobin (show MB Proteins) has a cell-membrane-penetrating activity similar to zebrafish Ngb.

  4. Neuroglobin appears to be associated with mitochondria-rich cell types and thus oxygen consumption rates, suggesting a myoglobin (show MB Proteins)-like function of this protein in facilitated oxygen diffusion

  5. both zebrafish and chimeric ZHHH Ngb can penetrate cell membranes in the absence of Chariot

Rabbit Neuroglobin (NGB) interaction partners

  1. Ngb overexpression may have potential therapeutic benefits for both reducing secondary damages and improving the outcomes after traumatic spinal cord injury

Neuroglobin (NGB) Protein Profile

Protein Summary

This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.

Gene names and symbols associated with Neuroglobin Proteins (NGB)

  • neuroglobin (NGB)
  • neuroglobin (Ngb)
  • neuroglobin (ngb)
  • neuroglobin L homeolog (ngb.L)
  • ngb protein

Protein level used designations for Neuroglobin Proteins (NGB)

neuroglobin

GENE ID SPECIES
58157 Homo sapiens
64242 Mus musculus
85382 Rattus norvegicus
414438 Sus scrofa
414920 Bos taurus
428896 Gallus gallus
442944 Canis lupus familiaris
443260 Ovis aries
467518 Pan troglodytes
594898 Xenopus (Silurana) tropicalis
641331 Macaca mulatta
641332 Monodelphis domestica
734191 Xenopus laevis
100000711 Danio rerio
100008868 Oryctolagus cuniculus
100379566 Cavia porcellus
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