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Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Additionally we are shipping Nuclear Prelamin A Recognition Factor-Like Antibodies (53) and Nuclear Prelamin A Recognition Factor-Like Kits (10) and many more products for this protein.
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we concluded that the Ser161Ile mutant induced NARFL deficiency and eventually diffuse PAVMs probably through VEGF (show VEGFA Proteins) pathway. In a word, we detected a functional mutation in NARFL, which might be the pathogenic gene in this pedigree.
MMS19 (show MMS19 Proteins) interacts with target proteins. MIP18 (show FAM96B Proteins) has a role to bridge MMS19 (show MMS19 Proteins) and CIAO1 (show CIAO1 Proteins). CIAO1 (show CIAO1 Proteins) also binds IOP1.
IOP1 is involved in mammalian cytosolic Fe-S protein (show CDSN Proteins) maturation.
human IscA1 (show ISCA1 Proteins) plays an important role in both mitochondrial and cytosolic iron-sulfur cluster biogenesis, and a notable component of the latter is the interaction between IscA1 (show ISCA1 Proteins) and IOP1.
knock-out of Iop1/Narfl in mice results in lethality and defective cytosolic iron-sulfur cluster assembly. The findings demonstrate an essential role for IOP1 in this pathway.
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity).
nuclear prelamin A recognition factor-like
, LET1 like/JFP15
, cytosolic Fe-S cluster assembly factor NARFL
, iron-only hydrogenase-like protein 1
, nuclear prelamin A recognition factor-like protein
, protein related to Narf
, cytosolic Fe-S cluster assembly factor narfl