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Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Additionally we are shipping and many more products for this protein.
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Zebrafish (Danio rerio) Polyclonal PAX2A Primary Antibody for WB - ABIN1881634
Krauss, Johansen, Korzh, Fjose: Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis. in Development (Cambridge, England) 1992
Show all 2 Pubmed References
Pax2a and Pax8 (show PAX8 Antibodies) regulate cell differentiation during sensory placode formation
Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development
pax8 (show PAX8 Antibodies) works with related genes pax2a/pax2b to downregulate otic expression of foxi1 (show FOXI1 Antibodies), a necessary step for further otic development
wnt1 (show WNT1 Antibodies) and wnt10b (show WNT10B Antibodies) are required to maintain threshold levels of Pax2.1 and Fgf8 (show FGF8 Antibodies) at the midbrain-hindbrain boundary.
hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors.
Pax2a and Pax8 (show PAX8 Antibodies) are the main effectors downstream of Fgf signals in ear formation
pax8 (show PAX8 Antibodies) is initially required for normal otic induction, and subsequently pax8 (show PAX8 Antibodies), pax2a and pax2b act redundantly to maintain otic fate
Pax2 (show PAX2 Antibodies)/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons.
Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation.
no isthmus protein
, paired box gene 2.1
, paired box homeotic gene 2a
, paired box protein Pax-2a