anti-Phospholipid Transfer Protein (PLTP) Antibodies

Maize/Corn (Zea mays) Phospholipid Transfer Protein (PLTP) interaction partners

1. identification and characterization of CaM-binding domain of non-specific lipid transfer proteins

Human Phospholipid Transfer Protein (PLTP) interaction partners

1. PLTP activity did not affect this metric. Thus, deviations in PLTP activity from the wild-type level reduce HDL (show HSD11B1 Antibodies) mass and ex vivo cholesterol efflux capacity, but not the rate of macrophage cholesterol efflux to plasma or in vivo mRCT.

2. serum CETP (show CETP Antibodies) and PLTP activity in patients diagnosed with hypothyroidism, was examined.

3. PLTP may regulate cigarette smoke extract-induced IL-8 expression via the ERK1/2 signaling pathway in human pulmonary epithelial cells

4. LPL (show LCP1 Antibodies) and PLTP appear to be novel glioma-associated proteins and play a role in the progression of human glioma

5. association of PON-1 (show PON1 Antibodies) activity with PLTP activity was lost in analysis which included large HDL (show HSD11B1 Antibodies) particles

6. a novel association between PLTPa and PON1 (show PON1 Antibodies) activity

7. The domain of apolipoprotein E4 required for PLTP activation resides within its amino-terminal 1-185 region.

8. Elevated baseline plasma levels of PLTP are associated with an increased risk of long-term all-cause mortality in patients with diabetes and known or suspected coronary disease.

9. This review summarizes the recent progresses made in the PLTP research field and focuses on the complexity of the implication of PLTP in obesity, insulin (show INS Antibodies) resistance and type 2 diabetes mellitus. [review]

10. Elevated plasma PLTP activity may predict an increased risk of T2DM in men

Mouse (Murine) Phospholipid Transfer Protein (PLTP) interaction partners

1. this work reports a physiological role for PLTP in the polarization of CD4 (show CD4 Antibodies)(+) T cells toward the pro-inflammatory Th1 (show HAND1 Antibodies) phenotype.

2. these findings elucidated that PLTP repressed LPS (show TLR4 Antibodies) induced inflammation due to extracellular LPS (show TLR4 Antibodies) binding capability, and the protective effects were not related to HDL (show HSD11B1 Antibodies) pool size in mice.

3. Data presented a novel model to link phospholipid metabolism to APP (show APP Antibodies) processing and also suggested that PLTP played an important role in Abeta (show APP Antibodies) metabolism and would be useful to further elucidate functions of PLTP in Alzheimer's disease susceptibility.

4. In hepatocytes, initial recruitment of phospholipid (PL) by apoB (show APOB Antibodies):1000 leading to the formation of the PL-rich apoB (show APOB Antibodies)-containing initiation complex is mediated to a large extent by PLTP.

5. PLTP plays an important role in modulating the stability of atherosclerotic plaques. The receptor-interacting protein 3 (show RIPK3 Antibodies)- reactive oxygen species signal pathway could be involved in this PLTP-mediated process.

6. Adipocyte PLTP plays a small but significant role in plasma PLTP activity and promotes cholesterol efflux from adipose tissues.

7. PLTP exerts significant effects on apoA-I (show APOA1 Antibodies) lipidation and nascent HDL (show HSD11B1 Antibodies) biogenesis in hepatocytes by promoting ATP-binding cassette transporter A1 (show ABCA1 Antibodies)-mediated lipid efflux and the remodeling of nascent HDL (show HSD11B1 Antibodies) particles.

8. Plasma Sphingosine-1-phosphate contents were decreased by 60.1 % in PLTP knockout mice (PLTP-/-, N = 5) compared with their wild type littermates (WT, N = 5) (151.70 +/- 38.59 vs. 379.32 +/- 59.90 nmol/l, P<0.01).

9. Therefore we concluded that PLTP deficiency impaired cognition and aggravated AD by enhancing the generation of Abeta (show APP Antibodies) in the cortex of old mice.

10. Cerebrovascular oxidative stress increased in PLTP deficient mice, including increased levels of reactive oxygen species (ROS) and lipid peroxidation marker 4-hydroxy-2-nonenal (HNE) and reduced superoxide dismutase (SOD) activity.

Pig (Porcine) Phospholipid Transfer Protein (PLTP) interaction partners

1. PLTP is actively involved in lipid transfer, cholesterol efflux, HDL (show HSD11B1 Antibodies) genesis, and remodeling at the blood-brain barrier.

Cow (Bovine) Phospholipid Transfer Protein (PLTP) interaction partners

1. Results suggest that phospholipid transfer protein (PLTP) polymorphisms might be an important genetic influence on economic traits in Hanwoo (Korean cattle).