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May play a role in tumor angiogenesis..
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The genetic variant near the PLXDC2 gene was found to influence the risk of POAG by increasing IOP in the Japanese population.
PLXDC1 (show PLXDC1 Proteins) and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF (show SERPINF1 Proteins).
We identified a genetic association for susceptibility to retinopathy in 5 novel chromosomal regions and PLXDC2 and ARHGAP22 (show ARHGAP22 Proteins), the latter 2 of which are genes implicated in endothelial cell angiogenesis and increased capillary permeability.
May play a role in tumor angiogenesis.
plexin domain containing 2
, plexin domain-containing protein 2
, plexin domain-containing protein 2-like
, tumor endothelial marker 7-related protein
, tumor endothelial marker 7 related