Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) Proteins (PTPN13)

The protein encoded by PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPN13 Antibodies (54) and PTPN13 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTPN13 5783 Q12923
PTPN13 19249 Q64512
PTPN13 498331  
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Top PTPN13 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$3,008.50
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$566.00
Details
Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$614.00
Details
Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$630.00
Details
Escherichia coli (E. coli) Human GST tag   5 μg Log in to see 10 to 12 Days
$352.75
Details

PTPN13 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) Interaction Partners

Human Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) interaction partners

  1. we found that miR-26a confers epidermal growth factor receptor-targeted tyrosine kinase inhibitors resistance of non-small cell lung cancer cells by targeting and silencing PTPN13

  2. Fap1 inhibition increased Fas sensitivity and decreased beta-catenin activity in human CD34+ CML cells

  3. the crystal structure of the PTP-Bas PDZ1 domain at 1.6 A resolution, is reported.

  4. PTPN13 overexpression significantly inhibited the progression of HCC (show FAM126A Proteins) cells.

  5. Mutation in PTPN13 gene is associated with gastric cancer peritoneal carcinomatosis.

  6. This work studied heat diffusion in the well-known PDZ-2 protein, and confirmed that this protein has two cognate allosteric pathways and that heat flows preferentially through these.

  7. Necl-4 serves as a novel regulator for contact inhibition of cell movement and proliferation cooperatively with the VEGF receptor and PTPN13

  8. A PDZ-mediated interaction of PTPN13 and PTEN is described with possible relevance for tumor suppression.

  9. The effect of the viscogens sucrose, and glycerol on the kinetic response of a photoperturbed PTPN13 is investigated.

  10. A comprehensive molecular dynamics simulation study of the PDZ2 domain of human tyrosine phosphatase 1E in the ligand-bound and -free state, as well as the photoswitchable protein in the cis (show CISH Proteins) and trans states of the photoswitch

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) interaction partners

  1. contributions of Fap1 to tyrosine kinase inhibitors (TKI)resistance, CML blast crisis, and relapse after TKI discontinuation

  2. The data show that the levels of PTPN13 and beta-catenin (show CTNNB1 Proteins) must be strictly regulated by extracellular signaling to regulate hematopoietic stem cells attachment to the bone marrow niche and the balance between proliferation and quiescence.

  3. The study presents a detailed kinetics analysis of the interaction between PTP-BL PDZ2 domain and a peptide mimicking the PDZ binding motif of APC (show APC Proteins).

  4. SDCCAG3 (show SDCCAG3 Proteins) forms a complex with PTPN13. Interaction of SDCCAG3 (show SDCCAG3 Proteins) with PTPN13 is mediated via the FERM domain of PTPN13 and via the N-terminus of SDCCAG3 (show SDCCAG3 Proteins).

  5. Data indicate that Bcr-abl (show ABL1 Proteins) increases PTPN13 promoter activity in an Icsbp (show IRF8 Proteins)-dependent manner.

  6. Since PTPL1 catalytic activity is important for cell transformation, VCP (show vcp Proteins) regulation by PTPL1 might be important for tumorigenesis.

  7. These findings demonstrate a key role for PTP-BL in 3T3-L1 and mouse embryo fibroblasts-derived adipocyte differentiation that is independent of its enzymatic activity.

  8. Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL

  9. With delayed kinetics, ephrinB ligands recruit the cytoplasmic PDZ domain containing protein (show USH1C Proteins) tyrosine phosphatase PTP-BL and are dephosphorylated.

  10. FAP-1 has a role in binding to, and consequently inhibition of, Fas (show FAS Proteins) export to the cell surface

Xenopus laevis Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) interaction partners

  1. RSK2 (show RPS6KA3 Proteins) phosphorylates three sites in Cdc25C (show CDC25C Proteins) and also partially activates Cdc25C (show CDC25C Proteins).

PTPN13 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Gene names and symbols associated with PTPN13

  • protein tyrosine phosphatase, non-receptor type 13 (PTPN13)
  • tyrosine-protein phosphatase non-receptor type 13 (LOC100540743)
  • protein tyrosine phosphatase, non-receptor type 13 (ptpn13)
  • protein tyrosine phosphatase, non-receptor type 13 (Ptpn13)
  • cell division cycle 25C L homeolog (cdc25c.L)
  • AI324989 protein
  • cdc25 protein
  • cdc25-1-b protein
  • cdc25c protein
  • cdc25c-a protein
  • cdc25c-b protein
  • cdc25c.S protein
  • cdc25C2 protein
  • FAP-1 protein
  • hPTP1E protein
  • PNP1 protein
  • ptp protein
  • PTP-BAS protein
  • Ptp-bl protein
  • PTP1E protein
  • PTPL1 protein
  • PTPLE protein
  • PTPN13 protein
  • Ptpri protein
  • RIP protein
  • wu:fb50g04 protein
  • xcdc25c protein
  • zgc:162319 protein

Protein level used designations for PTPN13

fas-associated protein-tyrosine phosphatase 1 , hPTPE1 , protein-tyrosine phosphatase 1E , protein-tyrosine phosphatase PTPL1 , tyrosine-protein phosphatase non-receptor type 13 , protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) , protein tyrosine phosphatase, non-receptor type 13 , tyrosine-protein phosphatase non-receptor type 13-like , PTP36 , protein tyrosine phosphatase DPZPTP , protein tyrosine phosphatase PTP-BL , protein-tyrosine phosphatase RIP , tyrosine phosphatase , protein Tyr phosphatase , M-phase inducer phosphatase 1-B , cell division cycle 25 homolog C , cell division cycle 25C S homeolog , protein-tyrosine phosphatase BAS

GENE ID SPECIES
5783 Homo sapiens
422591 Gallus gallus
461359 Pan troglodytes
100144609 Felis catus
100455138 Pongo abelii
100477379 Ailuropoda melanoleuca
100521910 Sus scrofa
100540743 Meleagris gallopavo
100566747 Anolis carolinensis
100603082 Nomascus leucogenys
19249 Mus musculus
498331 Rattus norvegicus
398119 Xenopus laevis
560883 Danio rerio
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