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PCDH20 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. Additionally we are shipping PCDH20 Antibodies (54) and PCDH20 Kits (6) and many more products for this protein.
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low expression of PCDH20 was found to be associated with poor OS in HCC (show FAM126A Proteins) patients; hence, this protein represents a promising potential prognostic biomarker
Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 (show SLC28A3 Proteins) as good candidates for modulatory genes in the auditory system. [meta-analysis]
Study shows that PCDH20 expression is downregulated in nasopharyngeal carcinoma cells (NPC (show NPC1 Proteins)) and identified it as a functional tumor suppressor and an important antagonist of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling and EMT (show ITK Proteins), with frequent epigenetic inactivation in NPC (show NPC1 Proteins).
In conclusion, these data here strongly suggested that PCDH20 may act as a candidate tumour suppressor in hepatocellular carcinoma.
The gender difference in PCDH20 expression may reflect olfactory receptor expression differences for gender-specific social discrimination
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.
, protocadherin 13