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SPPL2B Proteins

SPPL2B encodes a member of the GXGD family of aspartic proteases.

5 results:

Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 20-578) protein (rho-1D4 tag) Protein

SPPL2B Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3121792
$5,588.29
Plus shipping costs $45.00 and $24.00 dry ice
0.25 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 50 to 55 Business Days

Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 26-174) protein (His tag) Protein

SPPL2B Origin: Human Source: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3077439
$5,702.88
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 30 to 35 Business Days

Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 20-168) protein (His tag) Protein

SPPL2B Origin: Mouse Source: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3121791
$5,702.88
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 30 to 35 Business Days

Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 492-592) protein (His tag) Protein

SPPL2B Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3077440
$7,167.70
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days

Signal Peptide Peptidase-Like 2B (SPPL2B) (AA 26-592) protein (rho-1D4 tag) Protein

SPPL2B Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3095641
$7,957.57
Plus shipping costs $45.00 and $24.00 dry ice
0.5 mg (More quantities available)
local_shipping Shipping to: United States
Delivery in 50 to 55 Business Days
  • Type Protein
    • Protein
  • Target Signal Peptide Peptidase-Like 2B (SPPL2B)
    • Signal Peptide Peptidase-Like 2B (SPPL2B)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Crystallization (Crys)
  • Reactivity
    • Human
    • Mouse
  • Images available
  • Host
    • Insect Cells
    • Escherichia coli (E. coli)
  • Binding Specificity
    • AA 20-168
    • AA 20-578
    • AA 26-174
    • AA 26-592
    • AA 492-592
  • Conjugate
    • Un-conjugated
    • His tag
    • rho-1D4 tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid

SPPL2B Protein Profile

Protein Summary

This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPPL2B

  • signal peptide peptidase-like 2 (sppl2) antibody
  • signal peptide peptidase like 2B (sppl2b) antibody
  • signal peptide peptidase like 2B S homeolog (sppl2b.S) antibody
  • signal peptide peptidase like 2B (SPPL2B) antibody
  • signal peptide peptidase like 2B (Sppl2b) antibody
  • signal peptide peptidase-like 2B (Sppl2b) antibody
  • 3110056O03Rik antibody
  • AW550292 antibody
  • IMP-4 antibody
  • IMP4 antibody
  • MGC147524 antibody
  • PSH4 antibody
  • PSL1 antibody
  • RGD1308556 antibody
  • SPPL2B antibody
  • wu:fc16e01 antibody
  • wu:fc85d12 antibody
  • zgc:136525 antibody

Protein level used designations for SPPL2B

signal peptide peptidase-like 2B , signal peptide peptidase-like protein 2 , SPP-like 2B , protein SPP-like 2B , protein SPPL2b , intramembrane protease 4 , presenilin homologous protein 4 , presenilin-like protein 1

GENE ID SPECIES
325540 Danio rerio
780336 Xenopus (Silurana) tropicalis
379574 Xenopus laevis
420056 Gallus gallus
56928 Homo sapiens
73218 Mus musculus
504285 Bos taurus
362828 Rattus norvegicus

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