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SLC22A16 encodes a member of the organic zwitterion transporter protein family which transports carnitine. Additionally we are shipping SLC22A16 Antibodies (28) and many more products for this protein.
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Allele C of ABCB1 and allele A of SLC22A16 tended to have a greater association with grade 3/4 febrile neutropenia.
Deletions in SLC22A16, a doxorubicin transporter, are associated with a failure to achieve event free survival in immunochemotherapy-treated diffuse large B-cell lymphoma.
findings may greatly contribute to the elucidation of the roles of the Oct (show Plxna2 Proteins) and Myc (show MYC Proteins) proteins in osteoblast direct reprogramming. The results may also lead to establishment of novel regenerative therapy for various bone resorption diseases
Knockdown of CT2 (show CTAG2 Proteins) reduced the growth and viability of acute myeloid leukemia (show BCL11A Proteins) cells with high expression of CT2 (show CTAG2 Proteins) (OCI-AML2 (show RUNX3 Proteins) and HL60), but not low expression. CT2 (show CTAG2 Proteins) knockdown reduced basal oxygen consumption without a concomitant increase in glycolysis.
Both gene and protein expression of OCT6 were decreased in both CDDP-resistant lung cancer cell lines compared with their expression in their respective parental cells.
cytotoxic assays, stable transfectants of leukemic Jurkat cells overexpressing SLC22A16 cells became significantly more sensitive to doxorubicin
Variant alleles in the ABCB1 (show ABCB1 Proteins), SLC22A16 and CYP2B6 (show CYP2B6 Proteins) genes are associated with response to AC therapy in the treatment of breast cancer.
identification, expression and function of human CT2 (show CTAG2 Proteins) as a carnitine transporter in testis mediating transport of l-carnitine
may be possible to use progestins to increase the response of endometrioid endometrial carcinoma with SLC22A16 expression to adriamycin-based chemotherapeutic regimens
SLC22A16 was abundantly expressed in clear-cell adenocarcinomaof the ovary.
This gene encodes a member of the organic zwitterion transporter protein family which transports carnitine. The encoded protein has also been shown to transport anticancer drugs like bleomycin (PMID: 20037140) successful treatment has been correlated with the level of activity of this transporter in tumor cells.
, carnitine transporter 2
, flipt 2
, fly-like putative organic ion transporter 2
, fly-like putative transporter 2
, organic cation transporter 6
, organic cation transporter OKB1
, organic cation/carnitine transporter 6
, solute carrier family 22 (organic cation transporter), member 16
, solute carrier family 22 member 16
, Solute carrier family 22 member 16