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Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Additionally we are shipping Solute Carrier Family 24 Member 3 Antibodies (36) and many more products for this protein.
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NCKX3 is abundantly expressed within the human endometrium at the transcriptional and translational levels, and its level is regulated by steroid hormones (particularly estradiol) during the human menstrual cycle.
Plasma membrane ion transporter.Displayed K(+)-dependent Na(+)/Ca(2+) exchanger activity when assayed in heterologous expression systems, using digital imaging of fura-2 fluorescence, electrophysiology, or radioactive (45)Ca(2+) uptake.
NCKX3 may play a role in regulating calcium homeostasis.
The results of the present study indicate that NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones E2 and P4.
Suggest that a high level of renal NCKX3 expression maintain in distal convoluted tubules may play a role in active calcium transport in the kidneys of female mice.
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001
Na(+)/K(+)/Ca(2+)-exchange protein 3
, sodium calcium exchanger
, sodium/potassium/calcium exchanger 3
, solute carrier family 24 member 3
, potassium-dependent sodium-calcium exchanger NCKX3 (SLC24A3)
, solute carrier family 24, member 3