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Plays a role in the regulation of cell morphology and cytoskeletal organization. Additionally we are shipping STRIP2 Antibodies (12) and STRIP2 Proteins (4) and many more products for this protein.
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Data indicate that a cardiac protein named Myoscape/FAM40B/STRIP2, which directly interacts with the L-type calcium channel CaV1.2.
this study propose that the STRIPAK complex, FAM40A, FAM40B and STRN3, regulates the mode of cancer cell migration by controlling the activity of MST3 and 4, which locally coordinate the phosphorylation of ERM proteins and inhibit the dephosphorylation of MLC leading to increased actin-membrane linkage.
Myoscape/FAM40B/STRIP2 knockout (KO) mice display impairment of cardiac function progressing to advanced heart failure.
Fam40b is essential for the lineage commitment of murine embryonic stem cells into differentiated somatic cells.
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape (By similarity).
FAR11 factor arrest 11 homolog B
, family with sequence similarity 40, member B
, homolog of yeast FAR11 protein 2
, protein FAM40B
, striatin-interacting protein 2
, striatin-interacting proteins 2