anti-Sulfatase 2 (SULF2) Antibodies

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Additionally we are shipping Sulfatase 2 Kits (24) and Sulfatase 2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SULF2 55959 Q8IWU5
SULF2 72043 Q8CFG0
SULF2 311642  
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Top anti-Sulfatase 2 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated CyTOF, ELISA, FACS, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Sulfatase-2/SULF2 Antibody (2B4) [NBP1-36727] - Immunohistochemical analysis of Sulfatase 2 in non-small-cell lung carcinoma. (left) lung squamous cell carcinoma stained with 2B4 antibody and (right) tumor-associated stromal cells stained with 2B4 antibody. Image courtesy of Mark Singer at UCSF. Flow Cytometry: Sulfatase-2/SULF2 Antibody (2B4) [NBP1-36727] - Analysis using the FITC conjugate of NBP1-36727. Staining of Human lung cancer line with Sulfatase2-FITC. Image from verified customer review. 0.1 mL Log in to see 7 to 9 Days
$488.73
Details
Cow Rabbit Un-conjugated IHC, WB Human kidney 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated EIA, WB SULF2 Antibody (C-term) western blot analysis in human normal Uterus cell line lysates (35µg/lane).This demonstrates the SULF2 antibody detected the SULF2 protein (arrow). SULF2 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35µg/lane).This demonstrates the SULF2 antibody detected the SULF2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μg Log in to see 11 to 14 Days
$493.17
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details
Human Rabbit Un-conjugated WB SULF2 Antibody (C-term) (ABIN656715) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the SULF2 antibody detected the SULF2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat brain labeled with Anti-Sulfatase 2 Polyclonal Antibody, Unconjugated (ABIN750763) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Porcine Liver lysate; Primary Ab: 5µg/ml Rabbit Anti-Human SULF2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13 to 16 Days
$350.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Liver lysate; Primary Ab: 1µg/ml Rabbit Anti-Mouse SULF2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg Log in to see 13 to 16 Days
$360.00
Details

Top referenced anti-Sulfatase 2 Antibodies

  1. Human Monoclonal SULF2 Primary Antibody for CyTOF, ELISA - ABIN450044 : Lemjabbar-Alaoui, van Zante, Singer, Xue, Wang, Tsay, He, Jablons, Rosen: Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis. in Oncogene 2010 (PubMed)
    Show all 6 Pubmed References

  2. Rat (Rattus) Polyclonal SULF2 Primary Antibody for IF, WB - ABIN549061 : Nagamine, Koike, Keino-Masu, Masu: Expression of a heparan sulfate remodeling enzyme, heparan sulfate 6-O-endosulfatase sulfatase FP2, in the rat nervous system. in Brain research. Developmental brain research 2005 (PubMed)
    Show all 3 Pubmed References

  3. Rat (Rattus) Polyclonal SULF2 Primary Antibody for IF, WB - ABIN549062 : Ai, Do, Kusche-Gullberg, Lindahl, Lu, Emerson: Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. in The Journal of biological chemistry 2006 (PubMed)
    Show all 3 Pubmed References

  4. Cow (Bovine) Polyclonal SULF2 Primary Antibody for IHC, WB - ABIN2783715 : Uchimura, Morimoto-Tomita, Bistrup, Li, Lyon, Gallagher, Werb, Rosen: HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. in BMC biochemistry 2006 (PubMed)

  5. Human Polyclonal SULF2 Primary Antibody for ELISA, WB - ABIN4356740 : Dai, Yang, MacLeod, Yue, Rapraeger, Shriver, Venkataraman, Sasisekharan, Sanderson: HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. in The Journal of biological chemistry 2005 (PubMed)

More Antibodies against Sulfatase 2 Interaction Partners

Zebrafish Sulfatase 2 (SULF2) interaction partners

  1. Sulf2 expression is almost entirely restricted to the CNS.

Human Sulfatase 2 (SULF2) interaction partners

  1. High SULF2 expression is associated with glioma.

  2. The activity of sulfatase 2, a major form of endosulfatase in hepatocellular carcinoma can be studied, in connection with the interactions between heparan sulfate and various growth factors.

  3. SULF2 promotes the growth and metastasis of CRC probably by activating Akt and Erk1/2 pathways.

  4. Although no change in SULF2 was detected in squamous cell carcinoma of the head and neck (HNSCC) serum, its detection in saliva makes it worthy of further investigation as a potential HNSCC biomarker.

  5. results demonstrated that SULF2 can mediate the detrimental effects of ionizing radiation in vivo

  6. The short variants of Sulf2 promoted FGF2-induced MDA-MB231 and MCF7 in vitro growth while full-length Sulf1 inhibited growth supporting in vivo mammary tumour cell signalling patterns of growth.

  7. Most pancreatic ductal adenocarcinomas had positive SULF2 staining in tumour cells and intratumoural or tumour-adjacent stroma. Elevated SULF2 in PDAC was associated with advanced tumour stage, vascular invasion, shorter interval to radiological progression and shorter overall survival.

  8. The SULF1/SULF2 activation thus does not only promote regulated foetal growth and injury-induced liver regeneration but also dysregulated tumour growth.

  9. Sulf2 facilitated lymphangiogenesis in breast cancer cells by regulating VEGF-D and that the AKT1related signaling pathway was involved.

  10. renal cell carcinoma with lower SULF-2 expression might have a higher potential for cell invasion and proliferation, leading to a poorer prognosis via the activation of VEGF and/or FGF signaling

  11. SULF2 is a multifaceted protein involved in triglyceride-rich lipoprotein homeostasis and angiogenesis. [review]

  12. Our data confirmed that Sulf2 promoted breast cancer progression and regulated the expression of tumor-related genes in breast cancer.

  13. Tumor expression of SULF2 may affect prognosis in NSCLC, while blood SULF2 levels may have a significant role in the diagnosis of this fatal disease.

  14. SULF2 have a pro-tumorigenic effect in DU-145 and PC3 cancer cells, suggesting an important role of this enzyme in prostatic cancer metastasis.

  15. Results show that SULF1 or SULF2 overexpression contributes to colorectal cancer cell proliferation, migration, and invasion.

  16. Substrate specificity of human SULF2.

  17. SULF2 blood levels increased with age in both healthy and cirrhosis patients.SULF2 blood level was higher in cirrhosis patients than healthy individuals.

  18. pectin induced the expression of HSulf-2 through the interaction with fibronectin, alpha5beta1 integrin, and ERK1/2

  19. SULF2 expression in human tumor tissue and cell lines, was assessed.

  20. Our findings define Sulf-2 as a novel positive regulator of neuroblastoma pathogenicity that contributes to MYCN oncogenicity.

Mouse (Murine) Sulfatase 2 (SULF2) interaction partners

  1. Shh signaling requires the coordinated activity of Sulf1 and Sulf2 in order to reach that threshold in the mouse ventral spinal cord

  2. sulfate 6-O-endosulfatase 2 expression in type II alveolar epithelial cells plays a protective role in epithelial injury, inflammation and mortality

  3. Sulf1 and Sulf2 play indispensable roles to maintain glomerular integrity and protective roles in diabetic nephropathy, probably by growth factor modulation.

  4. Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.

  5. It is proposed that Sulf1, Sulf2 and ErbB1 are involved in the inhibition of neurite outgrowth and may regulate structural plasticity and regeneration in the nervous system.

  6. Sulf1/, but not Sulf2/, mice, exhibited a marked delay in healing of corneal epithelial wounds.

  7. SULF2 regulates tissue regeneration in part via the activation of a novel WNT-GLI1-CYCLIN D1 pathway.

  8. Sulf1 and Sulf2 differentially contribute to the generation of organ-specific sulfation patterns of heparan sulfate.

  9. Heparan sulfate sulfatase SULF2 regulates PDGFRalpha signaling and growth in human and mouse malignant glioma

  10. Sulf-1 and Sulf-2 are essential regulators of GDNF signaling in the SSC niche and direct downstream targets of Sertoli cell-specific transcriptional factor Wilm's tumor 1.

  11. SULF2 is an unexpected suppressor of atherogenic lipoprotein clearance by hepatocytes

  12. These results reveal that Sulf1 and Sulf2 fulfil non-redundant functions in vivo in the development and maintenance of the murine nervous system.

  13. results show that Sulf1 and Sulf2 play overlapping yet critical roles in mouse development and are redundant and essential for neonatal survival

  14. Sulfs are extracellular endosulfatases with strong potential for modulating the interactions of heparan sulfate proteoglycans in the extracellular microenvironment

  15. Sulf2 may have roles in several tissues but that there is compensation by and/or redundancy with Sulf1.

  16. SULF1 is expressed in GDNF-expressing esophageal muscle and SULF2 in innervating neurons, establishing their direct functions in esophageal innervation.

  17. Results establish Sulfs 1 and 2 as essential regulators of heparan sulfate-dependent growth factor signaling in the adult muscle stem cell niche.

  18. Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 in fine-tuning rather than regulating the development of skeletal structures.

  19. has an oncogenic effect in hepatocellular carcinoma, mediated in part through up-regulation of fibroblast growth factor signaling and glypican 3 expression

  20. Sulf1 and Sulf2 are two heparan sulfate 6-O-endosulfatases that regulate the activity of multiple growth factors, such as fibroblast growth factor and Wnt, and are essential for mammalian development and survival

Sulfatase 2 (SULF2) Antigen Profile

Protein Summary

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005

Gene names and symbols associated with anti-Sulfatase 2 (SULF2) Antibodies

  • sulfatase 2a (sulf2a) antibody
  • sulfatase 2 (SULF2) antibody
  • extracellular sulfatase Sulf-2 (LOC100540921) antibody
  • sulfatase 2 (sulf2) antibody
  • sulfatase 2b (sulf2b) antibody
  • sulfatase 2 S homeolog (sulf2.S) antibody
  • sulfatase 2 (Sulf2) antibody
  • 2010004N24Rik antibody
  • AU020235 antibody
  • HSULF-2 antibody
  • mKIAA1247 antibody
  • MSulf-2 antibody
  • si:dkeyp-84g9.1 antibody
  • Sulf1 antibody
  • SULF2 antibody
  • wu:fb48e04 antibody
  • xtsulf2 antibody
  • zgc:55612 antibody

Protein level used designations for anti-Sulfatase 2 (SULF2) Antibodies

sulfatase 2 , extracellular sulfatase Sulf-2-like , extracellular sulfatase Sulf-2 , sulf2a , sulfatase FP2a , sulfatase FP2b , sulfatase FP2

GENE ID SPECIES
393910 Danio rerio
715937 Macaca mulatta
100029594 Monodelphis domestica
100056840 Equus caballus
100392416 Callithrix jacchus
100482124 Ailuropoda melanoleuca
100540921 Meleagris gallopavo
100559066 Anolis carolinensis
100587072 Nomascus leucogenys
322056 Danio rerio
55959 Homo sapiens
495271 Xenopus laevis
419209 Gallus gallus
477254 Canis lupus familiaris
533264 Bos taurus
72043 Mus musculus
311642 Rattus norvegicus
100152351 Sus scrofa
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