Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Contributes to the lung's defense against inhaled microorganisms. Additionally we are shipping Surfactant Associated Protein D Kits (22) and Surfactant Associated Protein D Proteins (11) and many more products for this protein.
Showing 10 out of 15 products:
The results suggest that the c.917G>A (p.R306Q) mutation in the HOXD13 (show HOXD13 Antibodies) gene, may be responsible for syndactyly type Ic in this family.
Studied predictive value of surfactant protein D (SP-D) in lung cancer patients with interstitial lung disease induced by anticancer agents (ILD-AA). Results suggest that SP-D level change was a risk factor for mortality in patients with ILD-AA, and that SP-D might be a predictive prognostic biomarker of ILD-AA.
SP-D also delays FasL (show FASL Antibodies)-induced death of primary human T cells. SP-D delaying the progression of the extrinsic pathway of apoptosis could have important implications in regulating immune cell homeostasis at mucosal surfaces
findings suggest that these pulmonary markers could be useful to assess CAP severity and, especially YKL-40 (show CHI3L1 Antibodies) and CCL18 (show CCL18 Antibodies) by helping predict CAP caused by atypical pathogens
Knock down of the dickkopf (show DKK1 Antibodies) WNT (show WNT2 Antibodies) signaling pathway inhibitor 2 (DKK2 (show DKK2 Antibodies)) resulted in a significant suppression of HOXD10 (show HOXD10 Antibodies), HOXD11 (show HOXD11 Antibodies) and HOXD13 (show HOXD13 Antibodies) while over-expression of DKK2 (show DKK2 Antibodies) and stimulation with factors of the WNT (show WNT2 Antibodies) signaling pathway.
Trimeric SP-D wildtype recognized larger LPS (show IRF6 Antibodies) inner core oligosaccharides with slightly enhanced affinity than smaller compounds suggesting the involvement of stabilizing secondary interactions.
rs2819096 in the surfactant protein D (SFTPD) gene was associated with a higher risk of COPD (show ARCN1 Antibodies) GOLD III + IV.
SP-D increases the formation of nuclear and membrane blebs. Inhibition of caspase-8 (show CASP8 Antibodies) confirms the effect of SP-D is unique to the caspase-8 (show CASP8 Antibodies) pathway.
Findings indicate serum pulmonary surfactant protein D (SP-D, SFTPD) level as a potential marker to estimate the efficacy of epidermal growth factor receptor (EGFR (show EGFR Antibodies))-tyrosine kinase (show TXK Antibodies) inhibitor (TKIs).
Patients with SP-D 11Thr/Thr (show TRH Antibodies) genotype were more susceptible to acute kidney injury (AKI). Compared with healthy controls, serum SP-D levels at day 1, 3 and 7 were significantly elevated in AKI patients.
Elevation of SP-D is found in bronchoalveolar lavage fluid from inoculated lobes of calves infected with bovine adenovirus type 3.
The bSP (show KLK6 Antibodies)-D gene has 9 exons spanning about 10.5 kb on chromosome 28 at position q1.8. The 5'-upstream sequence has cis (show CISH Antibodies)-regulatory elements. It has 2 (show HAS2 Antibodies) polymorphisms in the carbohydrate recognition domain (242 Glu (show DCTN1 Antibodies)/Val & 268 Ala/Gly).
The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D.
Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety.
The presence of SP-D in endothelial cells which is NO-, PI(3 (show PI3 Antibodies))K/Akt (show AKT1 Antibodies)- and Erk (show MAPK1 Antibodies)-dependent is demonstrated. It suggests a protective role of SP-D in these cells.
The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen.
The data provide evidence SP-A (show SFTPA1 Antibodies) and SP-D attenuate S. aureus pneumonia severity resulting in decreased intestinal mucosal injury, apoptosis, and inflammation.
In triple KO mice, the HO-induced lung injury was associated with decreased surfactant protein (SP) A (show SFTPA1 Antibodies) and SPC (show SFTPC Antibodies) but not SPB and SPD expression.
Our study provides comprehensive information regarding spatial and temporal expression of collectins (SP-A (show SFTPA1 Antibodies), SP-D and MBL-A (show Mbl1 Antibodies)) and their cellular sources in murine testis. Positive regulation by testosterone and alteration in their level upon LPS (show TLR4 Antibodies) challenge are clues relevant to suggest their involvement in testicular immune privilege.
Our data may promote further studies on the morphological development of the aging lung and the role of SP-D in this process.
The experimentally induced alterations were more severe in the SP-D(-/-) than in the WT mice, particularly with respect to the surfactant-storing lamellar bodies which were sometimes extremely enlarged in SP-D(-/-) mice.
these results demonstrate SP-D plays protective roles by inhibiting apoptosis and modulating NF-kappaB-mediated inflammation in CLP-induced acute pancreatic injury .
SP-A (show SFTPA1 Antibodies)/D double knock-out mice showed increased susceptibility to urinary tract infection
Human and murine data together indicate that SP-A, SP-D and MBL are synthesized in early gestational tissues, and may contribute to regulation of immune response at the feto-maternal interface during pregnancy.
The presence of SP-A (show SFTPA1 Antibodies) and SP-D in the murine decidua is likely to play a protective role against intrauterine infection during pregnancy.
our results demonstrate that SFTPD deficiency affects female fertility, highlighting roles for SFTPD in ovarian and uterine physiology
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.
, lung surfactant protein D
, pulmonary surfactant apoprotein
, pulmonary surfactant-associated protein D
, surfactant, pulmonary-associated protein D
, surfactant-associated protein, pulmonary 4
, homeo box 4I
, homeo box D13
, homeobox protein Hox-4I
, homeobox protein Hox-D13
, pulmonary surfactant protein D
, surfactant associated protein D