anti-Transmembrane Protein 59 (TMEM59) Antibodies

Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Additionally we are shipping TMEM59 Proteins (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TMEM59 100196907  
TMEM59 9528 Q9BXS4
TMEM59 56374 Q9QY73
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Top anti-TMEM59 Antibodies at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30 μg of whole cell lysate) A:A431, 12% SDS PAGE antibody diluted at 1:500 WB Image TMEM59 antibody detects TMEM59 protein by Western blot analysis. A. 50 µg rat kidney lysate/extract 10 % SDS-PAGE TMEM59 antibody , dilution: 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: TMEM59 Antibody [NBP1-32303] - A. 50 ug rat kidney lysate/extract 10 % SDS-PAGE TMEM59 antibody dilution: 1:1000 Western Blot: TMEM59 Antibody [NBP1-32303] - Sample(30 ug of whole cell lysate) A:A43112% SDS PAGE GTX104486 diluted at 1:500 100 μL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB   100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of TMEM59 in human kidney tissue lysate with TMEM59 polyclonal antibody  at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide. Immunohistochemical staining of human kidney cells with TMEM59 polyclonal antibody  at 2.5 ug/mL. 100 μg Log in to see 11 to 12 Days
$356.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated ELISA, FM, IHC, WB   100 μg Log in to see 1 to 2 Days
$394.90
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 2 to 3 Days
$522.50
Details
Human Rabbit Un-conjugated IHC (fp), WB   100 μL Log in to see 6 to 8 Days
$431.20
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg Log in to see 11 to 16 Days
$587.71
Details

Top referenced anti-TMEM59 Antibodies

  1. Human Polyclonal TMEM59 Primary Antibody for IHC, IHC (p) - ABIN442274 : Bakulski, Dolinoy, Sartor, Paulson, Konen, Lieberman, Albin, Hu, Rozek: Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex. in Journal of Alzheimer's disease : JAD 2012 (PubMed)

More Antibodies against TMEM59 Interaction Partners

Human Transmembrane Protein 59 (TMEM59) interaction partners

  1. Results provide evidence that DCF1 plays an important role in controlling neuroblastoma (NB) tumor viability, promoting cell apoptosis, and inhibiting tumorigenesis in vivo. DCF1 could be a potential new inhibitor for components of the ERK1/2 signaling pathway and helped understand the molecular mechanism of NB.

  2. identify the single-span membrane protein TMEM59 as an interactor of FZD and LRP6 and a positive regulator of Wnt signaling. Mechanistically, TMEM59 promotes the formation of multimeric Wnt-FZD assemblies via intramembrane interactions.

  3. DCF1 subcellular localization and its function in mitochondria

  4. The TMEM59 gene identified from our discovery approach was recently implicated in amyloid-beta protein precursor post-translational processing, supporting a role for epigenetic change in LOAD pathology.

  5. TMEM59 affects amyloid precursor protein shedding by reducing its acccess to cellular components.

Mouse (Murine) Transmembrane Protein 59 (TMEM59) interaction partners

  1. Dcf1 triggers the dendritic spine and synaptic function through the recruitment of Lcn2 and activation of PSD95-NMDAR signaling.

  2. The Dcf1 knockout upregulates ATP1B1 expression in the hippocampus and DCF1 interaction with ATP1B1 in astrocytes impaired their structural plasticity.

  3. The results of this study revealed that DCF1-KO mice presented a visual behavioral deficit, higher GAD67 levels, and lower electrophysiological activity in V1 via the GABA system.

  4. Dcf1 plays an important role in behavior induced by the mushroom body in Drosophila and the dentate gyrus (DG) in mice and provides novel insights into their functions. Dcf1 rescued the optogenetic suppression of behavior by halorhodopsin in transgenic animals.

  5. Notably, we observed a significant increase in the ATP concentration in Dcf1(-/-) mice, suggesting a greater demand for energy in the absence of Dcf1. We studied the relationship between Dcf1 and NPY and revealed that Dcf1 plays a critical role in energy balance.

  6. This study shows that losing of dendritic cell factor 1 in the nervous system induces a social interaction deficit.

  7. MicroRNA-351 regulates TMEM 59 (DCF1) expression and mediates neural stem cell morphogenesis.

  8. The expression of tmem59 is an important factor contributing to Alzheimer's disease.

  9. Overexpression of the dcf1 gene, the NSCs were maintained in undifferentiated status. After the dcf1 gene was silenced, cells tended to differentiate into neurons and astrocytes.

Pig (Porcine) Transmembrane Protein 59 (TMEM59) interaction partners

  1. Chromosome mapping of 3 proteins (CRSP9, ETF1 and TMEM59) in swine

TMEM59 Antigen Profile

Protein Summary

Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding (By similarity).

Gene names and symbols associated with TMEM59

  • transmembrane protein 59 (tmem59) antibody
  • transmembrane protein 59 (Tmem59) antibody
  • transmembrane protein 59 (TMEM59) antibody
  • 1110001M20Rik antibody
  • 3110046P06Rik antibody
  • AI256529 antibody
  • C1orf8 antibody
  • D4Ertd20e antibody
  • HSPC001 antibody
  • MTDCF1 antibody
  • ORF18 antibody
  • Tmem59 antibody

Protein level used designations for TMEM59

transmembrane protein 59 , liver membrane-bound protein , thymic dendritic cell-derived factor 1

GENE ID SPECIES
566384 Danio rerio
100196907 Rattus norvegicus
9528 Homo sapiens
56374 Mus musculus
509775 Bos taurus
733610 Sus scrofa
479561 Canis lupus familiaris
100173202 Pongo abelii
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