anti-UBX Domain Protein 1 (UBXN1) Antibodies

Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Additionally we are shipping UBX Domain Protein 1 Proteins (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBXN1 51035 Q04323
UBXN1 225896 Q922Y1
UBXN1 293719  
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Top anti-UBX Domain Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBXN1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate WB Suggested Anti-UBXN1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Hela cell lysate  UBXN1 is supported by BioGPS gene expression data to be expressed in HeLa 100 μL 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated WB Western Blot analysis of UBXN1 expression in transfected 293T cell line by UBXN1 MaxPab polyclonal antibody.Lane 1: LOC51035 transfected lysate(34.32 KDa).Lane 2: Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB LOC51035 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Un-conjugated IP, WB   100 μg 11 to 14 Days
$925.83
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IP, WB   100 μL 11 to 14 Days
$595.83
Details
Cow Rabbit Un-conjugated IP   100 μL 11 to 14 Days
$595.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg 13 to 16 Days
$407.69
Details
Human Rabbit Un-conjugated IP, WB   100 μg 11 to 16 Days
$683.57
Details

More Antibodies against UBX Domain Protein 1 Interaction Partners

Human UBX Domain Protein 1 (UBXN1) interaction partners

  1. Our results identify how VCP is specifically targeted to ubiquitylated substrates in the BAG6 triage pathway and suggest that the degradation of ubiquitylated clients by the proteasome is reliant on the association of UBXN1 with ubiquitylated substrates and the catalytic activity of VCP.

  2. The ability of UBXN1 and other family members to negatively regulate the NFkappaB pathway may be important for dampening the host immune response in disease processes and also re-activating quiescent HIV from latent viral reservoirs in chronically infected individuals

  3. p47 promotes, whereas SASK1 delays the degradation of a single ERAD substrate, alpha-TCR. Additionally, we found that SAKS1 selectively inhibits the degradation of ERAD substrates without affecting cytosolic proteasomal substrates.

  4. UBXN1 is a negative regulator of NF-kappaB signaling.

  5. UBXN1 is induced and recruited to MAVS after virus infection, serving as a brake to prevent excessive RLR signaling, most likely at a late stage of infection.

  6. SAKS1 inhibits protein degradation mediated by p97 complexes in the cytosol with a component of the mechanism being the ability to shield polyubiquitin chains from ubiquitin-processing factors.

  7. Data suggest that UBXN1 regulates the enzymatic function of BRCA1 in a manner that is dependent on its ubiquitination status.

  8. Specific interaction of rat protein 2B28 with rat Homer2 may play a role in regulation of protein degradation by ubiquitin-proteasome systems and that this function may be specific to Homer2 proteins among Homer family proteins.

Mouse (Murine) UBX Domain Protein 1 (UBXN1) interaction partners

  1. Specific interaction of rat protein 2B28 with rat Homer2 may play a role in regulation of protein degradation by ubiquitin-proteasome systems and that this function may be specific to Homer2 proteins among Homer family proteins.

UBX Domain Protein 1 (UBXN1) Antigen Profile

Protein Summary

Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.

Gene names and symbols associated with UBXN1

  • UBX domain protein 1 (UBXN1) antibody
  • UBX domain protein 1 (Ubxn1) antibody
  • UBX domain protein 1 (ubxn1) antibody
  • 2B28 antibody
  • 4930455J02Rik antibody
  • D19Ertd721e antibody
  • fb49a05 antibody
  • RGD1309471 antibody
  • SAKS1 antibody
  • T25529 antibody
  • UBXD10 antibody
  • wu:fb49a05 antibody
  • zgc:77531 antibody

Protein level used designations for UBXN1

SAPK substrate protein 1 , UBA/UBX 33.3 kDa protein , UBX domain-containing protein 1 , mY33K , protein 2B28

GENE ID SPECIES
51035 Homo sapiens
225896 Mus musculus
293719 Rattus norvegicus
506676 Bos taurus
322073 Danio rerio
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