anti-UBX Domain Protein 6 (UBXN6) Antibodies

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. Additionally we are shipping UBXN6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBXN6 363332  
UBXN6 80700 Q9BZV1
UBXN6 66530 Q99PL6
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Top anti-UBXN6 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UBXN6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Muscle WB Suggested Anti-UBXN6  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UBXN6 Antibody (C-term) (ABIN651276) in mouse kidney tissue lysates (35 µg/lane).UBXN6 (arrow) was detected using the purified polyclonal antibody. UBXN6 Antibody (C-term) (ABIN651276) IHC analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$385.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Mouse Rabbit Un-conjugated WB Western Blot: UBXN6 Antibody [NBP1-98481] - Mouse Heart Lysate 1.0ug/ml, Gel Concentration: 12% 100 μL Log in to see 8 to 11 Days
$488.73
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: UBXN6 Antibody  - Staining of human testis shows nuclear and cytoplasmic positivity in cells in seminiferous ducts and Leydig cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Bat Rabbit Un-conjugated WB   50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC (p) Immunofluorescent staining of human cell line U-2 OS with UBXN6 polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleoli. Immunohistochemical staining of human testis with UBXN6 polyclonal antibody  shows strong cytoplasmic positivity in spermatids. 100 μL Log in to see 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of human pancreas with UBXN6 polyclonal antibody  shows strong nuclear and cytoplasmic positivity in exocrine glandular cells at 1:20-1:50 dilution. 100 μL Log in to see 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details

More Antibodies against UBXN6 Interaction Partners

Human UBX Domain Protein 6 (UBXN6) interaction partners

  1. These results indicate that the outer membrane protein MCL1 is degraded by the VCP-UBXD1 complex and that the process is promoted by the presence of mutant Huntingtin.

  2. Upon damage, p97 translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1, PLAA, and the deubiquitinating enzyme YOD1, which we term ELDR components for Endo-Lysosomal Damage Response.

  3. UBXD1-N intercalates into the p97-ND1 interface, thereby modulating interdomain communication of p97 domains and its activity with relevance for disease pathogenesis

  4. Data indicate that endosomal trafficking of CAV1 depends on ubiquitination of the N-terminal region and the subsequent recruitment of VCP-UBXD1.

  5. UBXD1 modulates the trafficking of ERGIC-53-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53.

  6. Data show that expression of VCP mutant proteins, or siRNA-mediated depletion of UBXD1 leads to a block of CAV1 transport at the limiting membrane of enlarged endosomes in cultured cells.

  7. UBXD1 is a novel co-factor of the human p97 ATPase.

  8. An additional p97 binding site in UBXD1 that competed with the p47 cofactor for binding to the N domain of p97 was identified.

  9. these findings suggest that UBXD1 is a regulatory component of endoplasmic reticulum-associated degradation that may modulate the adaptor binding to VCP.

Mouse (Murine) UBX Domain Protein 6 (UBXN6) interaction partners

  1. These results indicate that the outer membrane protein MCL1 is degraded by the VCP-UBXD1 complex and that the process is promoted by the presence of mutant Huntingtin.

UBXN6 Antigen Profile

Protein Summary

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation (By similarity).

Gene names and symbols associated with UBXN6

  • UBX domain protein 6 (Ubxn6) antibody
  • UBX domain protein 6 (UBXN6) antibody
  • 1200008L11Rik antibody
  • 2210415J11Rik antibody
  • AU040909 antibody
  • UBXD1 antibody
  • Ubxdc2 antibody

Protein level used designations for UBXN6

UBX domain containing 1 , UBX domain-containing protein 6 , UBX domain protein 6 , UBX domain-containing 1 , UBX domain-containing 2 , UBX domain-containing protein 1

GENE ID SPECIES
363332 Rattus norvegicus
715070 Macaca mulatta
100018491 Monodelphis domestica
100589901 Nomascus leucogenys
80700 Homo sapiens
66530 Mus musculus
507936 Bos taurus
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