anti-Ubiquitin-Fold Modifier 1 (UFM1) Antibodies

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1\; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M\; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Dec 2008].. Additionally we are shipping UFM1 Proteins (21) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UFM1 51569 P61960
UFM1 67890 P61961
UFM1 365797 Q5BJP3
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Top anti-UFM1 Antibodies at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-UFM1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis UFM1 using HT29 whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Western Blot: UFM1 Antibody [NBP1-79760] - Human Lung lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of human prostate with UFM1 polyclonal antibody  shows strong cytoplasmic positivity in glandular cells. 100 μL Log in to see 11 to 12 Days
$460.00
Details
Human Rabbit Un-conjugated WB Western Blot showing UFM1 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 50 μg Log in to see 6 to 8 Days
$473.93
Details
Human Rabbit HRP ELISA   100 μg Log in to see 11 to 18 Days
$668.03
Details
Human Rabbit FITC ELISA   100 μg Log in to see 11 to 18 Days
$668.03
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 18 Days
$668.03
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μg Log in to see 11 to 18 Days
$668.03
Details

More Antibodies against UFM1 Interaction Partners

Human Ubiquitin-Fold Modifier 1 (UFM1) interaction partners

  1. UFM1 His 70 resembles UBA5 (show UBA5 Antibodies) His336 and enters a negatively charged pocked on the other UFM1 molecule.

  2. These findings explicitly elucidate the role of UBA5 (show UBA5 Antibodies) dimerization in UFM1 activation.

  3. This study, focused on identifying the mutated gene in patients with hypomyelination with atrophy of the basal ganglia and cerebellum without TUBB4A (show TUBB5 Antibodies) mutations, revealed a homozygous 3-bp deletion in the UFM1 promoter area, which perfectly segregates with the disease.

  4. Meta analysis identified a new gene, UFM1, that is associated with low von Willebrand factor (show VWF Antibodies) levels.

  5. in the absence of UFSP2 (show C4orf20 Antibodies), a deconjugating enzyme for UFM1, ectopic expression of both UFL1 (show UFL1 Antibodies) and UFBP1, which serve as the E3-ligase complex for the UFM1-system, dramatically increases UFM1-conjugate formation at the endoplasmic reticulum.

  6. data imply that the combination of a hypomorphic p.Ala371Thr variant in trans with a loss-of-function allele in UBA5 underlies a severe infantile-onset encephalopathy

  7. Biallelic Variants in UBA5 (show UBA5 Antibodies) Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy

  8. results of an in vitro truncation assay suggest that Uba5 (show UBA5 Antibodies) residues 57-363 comprise the minimal fragment required for the high-efficiency activation of Ufm1

  9. ASC1 (show RPL3 Antibodies) is a target for ufmylation and that UFBP1 is an essential component for ASC1 (show RPL3 Antibodies) ufmylation.

  10. binding of ATP to Uba5 (show UBA5 Antibodies) approximately Ufm1 thioester was required for efficient transfer of Ufm1 from Uba5 (show UBA5 Antibodies) to Ufc1 (show UFC1 Antibodies) via transthiolation.

Mouse (Murine) Ubiquitin-Fold Modifier 1 (UFM1) interaction partners

  1. CNS-specific knockout of Ufm1 in mice causes neonatal death accompanied by microcephaly and apoptosis in specific neurons, further suggesting that the UFM1 system is essential for CNS development and function

  2. High UFM1 expression is associated with Atherosclerosis.

  3. transcription downregulation of the Ufm1 and FAT10 (show UBD Antibodies) conjugation system in liver Mallory-Denk bodies formation

  4. These data suggest that UFM1-UFBP1 participate in preventing ER stress-induced apoptosis in protein secretory cells.

  5. A novel type of E3 ligase for the Ufm1 conjugation system.

  6. A novel ubiquitin fold modifier (Ufm1) not been previously associated with ER stress and not found to be induced under any condition was found to be upregulated in the hearts of MCP (show CR1L Antibodies) mice (transgenic mice that express MCP-1 (show CPT1B Antibodies) specifically in the heart).

  7. loop between beta3 and alpha2 in addition to the C-terminal region of Ufm1 plays a role in binding to UfSP1

UFM1 Antigen Profile

Protein Summary

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1\; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M\; MIM 603173) (Komatsu et al., 2004

Gene names and symbols associated with UFM1

  • ubiquitin fold modifier 1 (UFM1) antibody
  • ubiquitin-fold modifier 1 (ufm1) antibody
  • ubiquitin-fold modifier (CCP2) antibody
  • ubiquitin fold modifier 1 (ufm1) antibody
  • ubiquitin-fold modifier 1 (Ufm1) antibody
  • ubiquitin-fold modifier 1 L homeolog (ufm1.L) antibody
  • ubiquitin-fold modifier 1 (PR46a) antibody
  • 1810045K17Rik antibody
  • AI132708 antibody
  • AI463323 antibody
  • bA131P10.1 antibody
  • BM-002 antibody
  • C13orf20 antibody
  • ENSMUSG00000074598 antibody
  • Gm10726 antibody
  • RGD1304890 antibody
  • T32E8.4 antibody
  • T32E8_4 antibody
  • ubfm1 antibody
  • wu:fa10f05 antibody
  • wu:fb72g01 antibody
  • zgc:55335 antibody

Protein level used designations for UFM1

ubiquitin-fold modifier 1

GENE ID SPECIES
452546 Pan troglodytes
477297 Canis lupus familiaris
549742 Xenopus (Silurana) tropicalis
695866 Macaca mulatta
844107 Arabidopsis thaliana
100528343 Ictalurus punctatus
51569 Homo sapiens
67890 Mus musculus
365797 Rattus norvegicus
530547 Bos taurus
418894 Gallus gallus
100286585 Salmo salar
100172209 Pongo abelii
495839 Xenopus laevis
322756 Danio rerio
5722153 Chlamydomonas reinhardtii
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