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Involved in transcriptional regulation. Additionally we are shipping Zinc Finger Protein 148 Proteins (4) and many more products for this protein.
Showing 10 out of 61 products:
Human Polyclonal ZNF148 Primary Antibody for WB - ABIN1882015
Udelhoven, Pasieka, Leeser, Krone, Schubert: Neuronal insulin receptor substrate 2 (IRS2) expression is regulated by ZBP89 and SP1 binding to the IRS2 promoter. in The Journal of endocrinology 2010
Show all 5 Pubmed References
Human Polyclonal ZNF148 Primary Antibody for ICC, IF - ABIN4367002
Sayin, Nilton, Ibrahim, Ågren, Larsson, Petit, Hultén, Ståhlman, Johansson, Bergo, Lindahl: Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment. in PLoS ONE 2013
Cow (Bovine) Polyclonal ZNF148 Primary Antibody for WB - ABIN2775856
Chupreta, Brevig, Bai, Merchant, Iñiguez-Lluhí: Sumoylation-dependent control of homotypic and heterotypic synergy by the Kruppel-type zinc finger protein ZBP-89. in The Journal of biological chemistry 2007
Show all 2 Pubmed References
The results indicate that the association with chr5p15.33-Region 2 may be explained by rs36115365, a variant influencing TERT (show TERT Antibodies) expression via ZNF148 in a manner consistent with elevated TERT (show TERT Antibodies) in carriers of the C allele.
ZNF148 as a gene involved in a newly described intellectual disability syndrome with a recurrent phenotype and postulate that the ZNF148 is a hitherto unrecognized but crucial transcription factor in the development of the corpus callosum.
A larger role ZBP-89 plays in gene regulation during inflammation.ZBP-89 regulates of MMP-1 (show MMP1 Antibodies) expression.ZBP-89 and NF-kappaB (show NFKB1 Antibodies) appear to bind cooperatively on both promoters.
ZBP-89 attenuates HDAC3 (show HDAC3 Antibodies) by increasing IkappaB degradation, dependent on Pin1 (show PIN1 Antibodies) but independent of NF-Kappab (show NFKB1 Antibodies)
zinc-binding protein (show PTMS Antibodies)-89 upregulates the expression of Bak (show BAK1 Antibodies) by targeting multiple components of the epigenetic pathway in hepatocellular carcinoma.
lower expression of ZNF148 in colorectal cancer was significantly associated with worse clinicopathologic variables, including lymph node metastases, poor differentiation, and a higher rate of disease recurrence
this study provides vigorous evidence that ZBP-89 was significantly downregulated in clear cell renal cell carcinoma (show MOK Antibodies)(CCRCC) and could be served as a promising biomarker for prediction of distal metastasis and prognosis of patient with CCRCC.
Colony formation was reduced dramatically in those hepatocellular carcinoma cell lines in which ZBP-89 overexpression was demonstrated; this appeared to correlate with increased apoptosis.
We found that the TP53 (show TP53 Antibodies)-G245D variant but not TP53 (show TP53 Antibodies)-R249S abrogated HDAC (show HDAC3 Antibodies) inhibitor p21 (show CDKN1A Antibodies) induction by binding to ZBP-89 and retaining it in the cytoplasm.
ZBP-89 is a regulator of Pdcd4 (show PDCD4 Antibodies) gene, binding to the basal promoter either alone or by interacting with Sp family members.
Data indicate zinc finger protein 148 (ZFP148) as a transcription factor that differentially binds to the zinc finger protein 30 protein (Zfp30) promoter region harboring rs51434084.
The results suggest that Zfp148 controls the fate of newly transformed intestinal tumor cells by repressing p53 (show TP53 Antibodies) and that targeting Zfp148 might be useful in the treatment of colorectal cancer.
Study demonstrated that miR (show MLXIP Antibodies)-20b suppressed ZFP-148 expression by directly binding to the 3'-UTR (show UTS2R Antibodies) of target mRNA and repressed translation at posttranscriptional level during virus myocarditis.
Zfp148 deficiency increases p53 (show TP53 Antibodies) activity and protects against atherosclerosis by causing proliferation arrest of lesional macrophages.
These data identify an important role for ZBP-89 in regulating stress hematopoiesis in adult mouse bone marrow.
Results indicate that Zfp148-deficient mice generate normal mature hematopoietic populations.
Zfp148 deficiency causes lung maturation defects and lethality.
ZBP-89 is required for expression of the Tph1 (show TPH1 Antibodies) gene and subsequent production of 5HT (show DDC Antibodies) in response to bacterial infection in mice. Reductions in epithelial ZBP-89 increase susceptibility to colitis and sepsis after infection with S. typhimurium.
MiR (show MLXIP Antibodies)-203 expression downregulated ZFP-148 mRNA translation by specifically targeting its 3' UTR (show UTS2R Antibodies), which resulted in differential expression of its downstream target genes, which in turn promote cell survival to foster Coxsackievirus B3 replication
ataxia telangiectasia mutated (show ATM Antibodies) protein phosphorylation of ZBP-89 contributes to Histone deacetylase (show HDAC1 Antibodies) inhibitors induction of p21(waf1 (show CDKN1A Antibodies)) gene expression
identify ZBP-89 as being a novel transcription factor involved in erythroid and megakaryocytic development and suggest that it serves a cooperative function with GATA-1 (show GATA1 Antibodies) and/or FOG-1 (show ZFPM1 Antibodies) in a developmental stage-specific manner
Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.
CACCC box-binding protein
, CLL-associated antigen KW-10
, transcription factor ZBP-89
, zinc finger DNA-binding protein 89
, G-rich box-binding protein
, beta enolase repressor factor 1
, transcription factor BFCOL1
, zinc finger binding protein 89
, zinc finger DNA binding protein 89
, solute carrier family 12 (potassium/chloride transporters), member 8
, zinc finger protein 148 (pHZ-52)