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May be involved in transcriptional regulation.
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Ectopic expression of ZNF23 induced cell apoptosis by activation of caspase-3 (show CASP3 Antibodies), p27 (show PAK2 Antibodies), p53 (show TP53 Antibodies) expression and down-regulation of Bcl-2 (show BCL2 Antibodies) through mitochondria-dependent pathway.
ZNF23 gene could play an important role in the development of hepatocellular carcinoma.
Characterization of ZNF359 and its role in human development
ZNF23 is a new member of KRAB-ZNF (show ZNF629 Antibodies) superfamily with growth-inhibitory ability and its downregulation may contribute to carcinogenesis
ZNF23 induced apoptosis partially via down-regulation of Bcl-XL (show BCL2L1 Antibodies).
May be involved in transcriptional regulation. May have a role in embryonic development.
kruppel-like zinc finger factor X31
, zinc finger protein 23 (KOX 16)
, zinc finger protein 32
, zinc finger protein 359
, zinc finger protein 612
, zinc finger protein KOX16