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Human Polyclonal ZNF350 Primary Antibody for ICC, IF - ABIN4367184
Hallen, Klein, Stoschek, Wehrmeyer, Nonhoff, Ralser, Wilde, Röhr, Schweiger, Zatloukal, Vingron, Lehrach, Konthur, Krobitsch: The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. in Human molecular genetics 2010
Results indicate ZNF350 as an important gene mammary oncogenesis.
Results indicated that SNP rs2278414 at ZNF350 may in fl uence an individual's susceptibility to age-related cataract (ARC (show NOL3 Antibodies)) by affecting the binding af fi nity of miR (show MLXIP Antibodies)-21-3p and miR (show MLXIP Antibodies)-150-5p and regulating expression levels of the mRNAs, resulting in different levels of cellular DNA breaks, thus contributing to ARC (show NOL3 Antibodies).
villin directly interacts with a transcriptional corepressor and ligand of the Slug promoter, ZBRK1.
ZBRK1 suppresses renal cancer progression perhaps by regulating VHL (show VHL Antibodies) expression through formation of a complex with VHL (show VHL Antibodies) and p300 (show EP300 Antibodies) in renal cancer
MAGE (show MAGEB10 Antibodies) proteins bind to KAP1 (show CDKN3 Antibodies), a gene repressor and ubiquitin E3 ligase which also binds KRAB domain containing zinc finger transcription factors (KZNFs), and MAGE (show MAGEB10 Antibodies) expression may affect KZNF mediated gene regulation.
The secondary structure of the ZBRK1-DNA complex is found to be significantly altered from the standard B-DNA conformation.
results indicate that a loss of ZBRK1 contributes to the increased expression of KAP1 (show CDKN3 Antibodies), potentiating its role to enhance metastasis and invasion
promoter assays in two breast cancer cell lines identified two haplotypes (H11 and H12 (show HIST1H1C Antibodies)) stimulating significantly the expression of ZNF350 transcript compared with the common haplotype H8
ZBRK1 negatively regulates the HIV-1 LTR
high levels of gene activity in the genomic environment and the pre-deposition of repressive histone marks within a gene increase its susceptibility to KRAB/KAP1 (show CDKN3 Antibodies)-mediated repression
Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3 (By similarity).
KRAB zinc finger protein ZFQR
, zinc finger and BRCA1-interacting protein with a KRAB domain 1
, zinc finger protein ZBRK1
, zinc-finger protein ZBRK1
, zinc finger protein 350
, zinc finger protein 350-like