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May be implicated in the gamete interaction during fertilization (By similarity). Additionally we are shipping ZPBP2 Antibodies (16) and ZPBP2 Kits (6) and many more products for this protein.
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modest changes (8-13%) in promoter methylation levels of ZPBP2 and GSDMA (show GSDMA Proteins) may cause substantial changes in RNA levels and allelic expression of ZPBP2 and ORMDL3 (show ORMDL3 Proteins) is mediated by DNA methylation (show HELLS Proteins)
The local genotype influences methylation levels at SLC22A5 (show SLC22A5 Proteins) and ZPBP2 promoters independently of the asthma status. Further studies are necessary to confirm the relationship between GSDMA (show GSDMA Proteins)-ZPBP2 and SLC22A5 (show SLC22A5 Proteins) methylation and asthma in females and males separately.
The allele T of rs10852936 surrounding the IKZF3 (show IKZF3 Proteins)-ZPBP2 locus confers risk for early-onset psoriasis.
allele-specific transcriptional regulation of genes in the asthma-associated chromosomal region 17q12-q21; rs4795397 influences activity of ZPBP2 promoter in an allele-dependent fashion and leads to nucleosome repositioning on the asthma-associated allele; methylation of exon 1 of ZPBP2 masks the genetic effect on ZPBP2 promoter; ORMDL3 (show ORMDL3 Proteins) promoter is unmethylated
Four additional susceptibility loci (IRF8 (show IRF8 Proteins), TMEM39A, IKZF3 (show IKZF3 Proteins), and ZPBP2) for systemic lupus erythematosus were robustly established a multiethnic population (European, African American, Asian, Hispanic, Gullah, and Amerindian).
The disease-linked haplotype and putative causal DNA variants of ZPBP2/GSDMB (show GSDMB Proteins)/ORMDL3 (show ORMDL3 Proteins) locus via a combination of genetic and functional analyses, were identified.
May be implicated in the gamete interaction during fertilization (By similarity).
zona pellucida binding protein 2
, zona pellucida-binding protein 2
, zona pellucida-binding protein 2-like
, ZPBP-like protein