gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 Proteins (GABRA3)

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA3 Antibodies (69) and GABRA3 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GABRA3 2556 P34903
GABRA3 14396 P26049
Rat GABRA3 GABRA3 24947  
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Top GABRA3 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,649.05
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,744.22
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,616.87
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

GABRA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
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Mouse (Murine) ,
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More Proteins for gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) interaction partners

  1. These small-molecule GlyR PAMs have high potential both as early tool compounds to enable pharmacological studies of GlyR inhibitory neurotransmission and as a starting point for the development of potent, selective GlyRalpha3 (show GLRa3 Proteins) PAMs as novel analgesics.

  2. GABA alpha2 and/or alpha3 receptor subtypes are involved in GABAergic modulation of prolactin (show PRL Proteins) secretion.

  3. GABRA3 induced MMP-2 (show MMP2 Proteins) and MMP-9 (show MMP9 Proteins) expression through activation of the JNK (show MAPK8 Proteins)/AP-1 (show FOSB Proteins) signaling pathway, promoting lymphatic metastasis in lung adenocarcinoma.

  4. Gabra3 activates the AKT (show AKT1 Proteins) pathway to promote breast cancer cell migration, invasion and metastasis. The A-to-I RNA-edited form of Gabra3 is found only in non-invasive breast cancers. Edited Gabra3 suppresses breast cancer cell invasion and metastasis.

  5. The N-terminal region of GABRA3 and the GlyR beta subunit (show POLG Proteins) occupies the same binding site of gephyrin (show GPHN Proteins).

  6. high expression of GABBR2 (show GABBR2 Proteins) with a low expression of GABR(A3) may predict a better outcome in non-small cell lung cancer

  7. A novel role for GA-repeat core promoter to regulate gene expression in the genes such as GABRA3 involved in development and evolution.

  8. We identified truncating mutations in distinct X-linked gamma-aminobutyric acid A (GABAA (show GABRg1 Proteins)) receptor subunit-encoding genes, GABRQ (show GABRQ Proteins) and GABRA3.this is the first report of ASD (show ARSD Proteins) patients with truncating mutations in GABA receptors genes.

  9. The results indicate that there may be specific GABA receptor gene expression variation in migraine, particularly involving the GABRA3 and GABBR2 (show GABBR2 Proteins) genes.

  10. The ratios of beta(3)/beta(2) and alpha(5)/alpha(1) subunit protein expression in Angelman syndrome (show ube3a Proteins) cortex were significantly decreased when compared with controls.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) interaction partners

  1. Absence of the Gabra3 receptor subunit slows recovery from ethanol-induced incoordination.

  2. Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice

  3. Despite the exclusive expression of alpha3-containing GABAA (show GABRg1 Proteins) receptors in the reticular thalamic nucleus, these receptors do not seem to be critical for the mediation of the effects of diazepam on the sleep EEG

  4. editing of the Gabra-3 mRNA is important for normal brain development.The extent of editing is low at birth but increases with age, reaching close to 100% in the adult brain.

  5. The phenotypes following global deletion of the GABAA (show GABRg1 Proteins) receptor alpha3 subunit provided relevant insights into the potential behavioural relevance of this specific receptor subtypes in the modulation of both affective and cognitive functions.

  6. Deletion of the GABAAR (show GABRG2 Proteins) alpha3 subunit reduces evoked thalamic oscillatory activity.

  7. Resutls show that the variation in editing gave receptors like HTR2C (show HTR2C Proteins) and GABA(A) (gamma-aminobutyric acid type A) a different set of protein isoforms during development from those in the adult animal.

Xenopus laevis gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) interaction partners

GABRA3 Protein Profile

Protein Summary

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Gene names and symbols associated with GABRA3

  • gamma-aminobutyric acid type A receptor alpha3 subunit (GABRA3)
  • gamma-aminobutyric acid receptor subunit alpha-3 (LOC100333913)
  • gamma-aminobutyric acid (GABA) A receptor, alpha 3 (gabra3)
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 (Gabra3)
  • gamma-aminobutyric acid type A receptor alpha3 subunit (Gabra3)
  • gamma-aminobutyric acid receptor subunit alpha-3 (LOC100653496)
  • Gabra-3 protein
  • GABRA3 protein
  • si:ch211-113k9.1 protein

Protein level used designations for GABRA3

GABA(A) receptor subunit alpha-3 , GABA(A) receptor, alpha 3 , gamma-aminobutyric acid receptor subunit alpha-3 , gamma-animobutyric acid (GABA) A receptor, alpha 3 , gamma-aminobutyric acid (GABA) A receptor, alpha 3 , gamma-aminobutyric acid A receptor, alpha 3 , gamma-aminobutyric acid A receptor, alpha 3-like , gamma-aminobutyric acid receptor subunit alpha-3-like , GABA-A receptor alpha-3 subunit , Gamma-animobutyric acid (GABA) A receptor alpha 3 , Gamma-animobutyric acid (GABA) A receptor, alpha 3 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3 , gamma-aminobutyric acid receptor, subunit alpha 3

GENE ID SPECIES
2556 Homo sapiens
282237 Bos taurus
422289 Gallus gallus
465914 Pan troglodytes
492223 Canis lupus familiaris
100063420 Equus caballus
100294524 Felis catus
100333913 Danio rerio
100349107 Oryctolagus cuniculus
100391222 Callithrix jacchus
100451835 Pongo abelii
100466765 Ailuropoda melanoleuca
100494398 Xenopus (Silurana) tropicalis
100592909 Nomascus leucogenys
14396 Mus musculus
24947 Rattus norvegicus
100653496 Xenopus laevis
100725783 Cavia porcellus
100538116 Danio rerio
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