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Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases (By similarity)..
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Human Polyclonal ARHGEF17 Primary Antibody for IHC, ELISA - ABIN1003259
Rümenapp, Freichel-Blomquist, Wittinghofer, Jakobs, Wieland: A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domain. in The Biochemical journal 2002
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Human Polyclonal ARHGEF17 Primary Antibody for IHC (p), WB - ABIN541326
Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: Cell surface tumor endothelial markers are conserved in mice and humans. in Cancer research 2001
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Polyclonal ARHGEF17 Primary Antibody for IHC (p), WB - ABIN540315
Chen, Hou, Tang, Jhuang, Lai, Lee, Kuo, Chou, Liu, Lin, Chuang, Chen, Tseng, Huang, Chiang, Lee, Liu, Liu, Yao, Huang, Ko, Hsu, Wu, Tsay, Chen, Tien: Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia. in PLoS ONE 2015
data implicate TEM4 as an essential regulator of the actin cytoskeleton that ensures proper membrane protrusion at the leading edge of migrating cells and efficient cellular migration via suppression of actomyosin contractility
Interaction of the central domain of ARHGEF17 with Mps1.
The rho guanine nucleotide exchange factor 17 is drastically alter the effect of cGMP/cGK involving signaling pathways on RhoA-activated downstream effectors.
TEM4 contains a novel actin binding domain and binding to actin is essential for TEM4 subcellular localization and activity.
a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart
Identification of ARHGEF17, mutations in melanoma.
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases (By similarity).
164 kDa Rho-specific guanine-nucleotide exchange factor
, Rho-specific guanine-nucleotide exchange factor 164 kDa
, rho guanine nucleotide exchange factor 17
, tumor endothelial marker 4