alpha-conotoxin GI (alpha conotoxin GI)
-
- Target
- alpha-conotoxin GI
- Application
- Blocking Reagent (BR)
- Purpose
- alpha-conotoxin G blocks nAChR receptors
- Sequence
- Glu-Cys2-Cys3-Asn-Pro-Ala-Cys7-Gly-Arg-His-Tyr-Ser-Cys13-NH2Disulfide bonds between Cys2-Cys7, Cys3-Cys13
-
- Restrictions
- For Research Use only
-
-
- Target
- alpha-conotoxin GI
- Background
- Alpha-conotoxin GI has been isolated from the venom of the cone snail Conus geographus. This conotoxin acts on postsynaptic membranes, which bind to the nicotinic acetylcholine receptor (nAChR). It Inhibits nAChR currents. The highestaffinity site for Cis the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ.
- Molecular Weight
- 1437.61 Da
- CAS-No
- 76862-65-2
-
You are here:
