BAFF and Receptor Detection Set
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- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
- Purification
- Antibodies are supplied as affinity chromatography purified IgG.
- Components
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BAFF Antibody, (50 μg)
APRIL Antibody, (50 μg)
TACI Antibody, (50 μg)
BCMA Antibody, (50 μg)
BAFF-R Antibody, (50 μg)
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- Application Notes
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These polyclonal antibodies can be used for detection of BAFF and its receptors by Western blot at 2 μg/mL to 1 μg/mL, Immunohistochemistry, and Immunoflourescence. Whole cell lysate from HepG2 cells can be used as a positive control for each antibody except BAFF-R antibody, murine spleen lysate can be used as a positive control for that.
Optimal dilutions for each application to be determined by the researcher. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Stable at 4 °C for three months, store at -20 °C for up to one year.
- Expiry Date
- 12 months
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- Background
- Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κB activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL, a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.
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