HDAC1 antibody (AA 469-480)

Catalog No. ABIN1101989

Product Details anti-HDAC1 Antibody

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Binding Specificity: AA 469-480

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Monkey, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This HDAC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human HDAC1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit, Guinea pig (100%) Dog, Bovine, Panda, Horse, Porcine (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KPEAKGVKEEVK from the C-terminus of human HDAC1 (NP_004955.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit, Guinea pig (100%), Dog, Bovine, Panda, Horse, Porcine (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:4000), WB (0.5 - 2 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Approx 55kD band observed in Human Lymph Node and Thymus lysates and approx 70kD band observed in lysates of cell lines HeLa and NIH3T3 (calculated MW of 55.1kD according to NP_004955.2). The observed 70kD band represents the sumoylated protein according to David et al, J Biol Chem. 2002 Jun 28,277(26):23658-63, PMID: 11960997. Recommended concentration: 0.5-2 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Alternative Name: HDAC1 (HDAC1 Products)

Synonyms: GON-10 antibody, HD1 antibody, RPD3 antibody, RPD3L1 antibody, CG7471 antibody, DHDAC1 antibody, DRpd3 antibody, DmHDAC1 antibody, Dmel\\CG7471 antibody, E(var)3-64BC antibody, HDAC antibody, HDAC-1 antibody, HDAC1 antibody, Hdac1 antibody, Rpd3/HDAC antibody, Su(var)3-26 antibody, Su(var)326 antibody, Su(var)328 antibody, dHDAC-1 antibody, dHDAC1 antibody, dRPD3 antibody, dRpd3 antibody, dmHDA401 antibody, drpd3 antibody, hdac1 antibody, l(3)04556 antibody, l(3)64Cc antibody, rpd3 antibody, rpd[3] antibody, gon-10 antibody, hdac1b antibody, rpd3l1 antibody, Rpd3 antibody, GB14706 antibody, hdac1-b antibody, chunp6919 antibody, hdac-1 antibody, mp:zf637-2-001987 antibody, wu:fb19h11 antibody, wu:fi06f03 antibody, zgc:101582 antibody, zgc:65818 antibody, Hdac1-ps antibody, MommeD5 antibody, ARABIDOPSIS HISTONE DEACETYLASE 1 antibody, ARABIDOPSIS HISTONE DEACETYLASE 19 antibody, ATHD1 antibody, ATHDA19 antibody, ATRPD3A antibody, F20D10.250 antibody, F20D10_250 antibody, HDA1 antibody, HDA19 antibody, HISTONE DEACETYLASE antibody, HISTONE DEACETYLASE 19 antibody, HISTONE DEACETYLASE19 antibody, RPD3A antibody, histone deacetylase 1 antibody, HDM antibody, ab21 antibody, hdac1a antibody, histone deacetylase 1 antibody, Histone deacetylase 1 antibody, histone deacetylase antibody, histone deacetylase 1 S homeolog antibody, histone deacetylase Rpd3 antibody, histone deacetylase 1 L homeolog antibody, HDAC1 antibody, hdac1.S antibody, LOC411503 antibody, hdac1 antibody, Hdac1 antibody, HD1 antibody, hda-1 antibody, hdac1.L antibody, LOC748850 antibody

Background: Name/Gene ID: HDAC1
Family: Histone Deacetylase

Synonyms: HDAC1, Histone deacetylase 1, GON-10, HD1, RPD3, RPD3L1

Gene ID: 3065

NCBI Accession: NP_004955

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis