TIAM2 antibody (AA 1899-1911)

Catalog No. ABIN1104689

Product Details anti-TIAM2 Antibody

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Binding Specificity: AA 1899-1911

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TIAM2 antibody is un-conjugated

Application: ELISA

Specificity: Human TIAM2. This antibody is expected to recognize all reported isoforms (NP_036586.2, NP_001010927.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Marmoset, Panda (100%) Orangutan, Gibbon, Monkey, Galago, Dog, Elephant, Horse (92%) Opossum, Guinea pig, Platypus (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QIRHQSLDSQSEN from an internal region of human TIAM2 (NP_036586.2, NP_001010927.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Marmoset, Panda (100%), Orangutan, Gibbon, Monkey, Galago, Dog, Elephant, Horse (92%), Opossum, Guinea pig, Platypus (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:32000)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx 70kD band in NIH3T3 lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 192kD according to Mouse NP_036008.2. The 70kD band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TIAM2

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Alternative Name: TIAM2 (TIAM2 Products)

Synonyms: STEF antibody, TIAM-2 antibody, 3000002F19Rik antibody, mKIAA2016 antibody, TIAM2 antibody, T-cell lymphoma invasion and metastasis 2 antibody, T cell lymphoma invasion and metastasis 2 antibody, T-cell lymphoma invasion and metastasis 2a antibody, T-lymphoma invasion and metastasis-inducing protein 2 antibody, TIAM2 antibody, Tiam2 antibody, tiam2a antibody, LOC100598161 antibody

Background: Name/Gene ID: TIAM2

Synonyms: TIAM2, KIAA2016, STEF, TIAM-2

Gene ID: 26230

NCBI Accession: NP_036586, NP_001010927

UniProt: Q8IVF5

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha