CDC6 antibody

Catalog No. ABIN1106638

Product Details anti-CDC6 Antibody

Target: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDC6 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to CDC6.

Purification: Affinity chromatography

Immunogen: Recombinant human Cdc6

Clone: IMD-6

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CDC6

Target: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Alternative Name: CDC6 (CDC6 Products)

Synonyms: CDC18L antibody, HsCDC18 antibody, HsCDC6 antibody, cell division cycle 6 antibody, CDC6 antibody, Cdc6 antibody

Background: Cell division sycle(CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34(cdc2)/cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53,000 daltons whose C-terminal domain shares about 37 % sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31.Synonyms: CDC18L, CDC6-related protein, Cdc18-related protein, Cell division control protein 6 homolog, HsCDC6, HsCdc18, p62(cdc6)

Gene ID: 990

NCBI Accession: NP_001245

UniProt: Q99741

Pathways: DNA Replication, Synthesis of DNA