IL-24 antibody

Catalog No. ABIN1107832

Product Details anti-IL-24 Antibody

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-24 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This Monoclonal antibody recognises both natural and recombinant Human IL-24 (Interleukin-24) also known as MDA-7 or TH2-specific cytokine FISP.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography

Immunogen: Recombinant Human IL-24. Myeloma X63/AG.8653 x Balb/c node cells.

Clone: B-C54

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS without carriers and preservatives

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Alternative Name: Interleukin-24 / IL24 (IL24 Products)

Synonyms: C49A antibody, FISP antibody, IL10B antibody, MDA7 antibody, MOB5 antibody, ST16 antibody, Mda7 antibody, St16 antibody, Mda-7 antibody, IL24 antibody, interleukin 24 antibody, IL24 antibody, Il24 antibody

Background: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein

Gene ID: 11009

NCBI Accession: NP_001172085

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy