KATNA1 antibody (C-Term)

Catalog No. ABIN1107914

Product Details anti-KATNA1 Antibody

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KATNA1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR

Cross-Reactivity (Details): Species reactivity (tested):Mouse, human.

Purification: Immunoaffinity column

Immunogen: Synthetic peptide directed towards the C-terminal region of mouse Katna1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for KATNA1

Target: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Alternative Name: KATNA1 (KATNA1 Products)

Synonyms: si:dkey-15j16.1 antibody, zgc:110580 antibody, katna1 antibody, katanin catalytic subunit A1 antibody, katanin p60 (ATPase containing) subunit A 1 antibody, katanin p60 (ATPase-containing) subunit A1 antibody, KATNA1 antibody, katna1 antibody, Katna1 antibody

Background: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.Synonyms: Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin

Molecular Weight: Katna1: 54 kDa

Gene ID: 23924

NCBI Accession: NM_011835

Pathways: Microtubule Dynamics