KIN antibody (Middle Region)

Catalog No. ABIN1107973

Product Details anti-KIN Antibody

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEKTAKFIEE QVRRGLEGKE QEVPTFTELS RENDEEKVTF NLSKGACSSS

Cross-Reactivity (Details): Species reactivity (expected):Rat, Dog, Mouse, Bovine, Chicken, African clawed frogSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-KIN antibody: synthetic peptide directed towards the middle region of human KIN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for KIN

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Alternative Name: KIN (KIN Products)

Synonyms: Kin17 antibody, BTCD antibody, KIN17 antibody, Kin17 DNA and RNA binding protein antibody, Kin17 DNA and RNA binding protein S homeolog antibody, Kin antibody, kin.S antibody, KIN antibody

Background: Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.Synonyms: BTCD, Binding to curved DNA, DNA/RNA-binding protein KIN17, KIN, KIN, KIN17, antigenic determinant of recA protein homolog

Gene ID: 22944

NCBI Accession: NP_036443