TFPI2 antibody (Middle Region)

Catalog No. ABIN1109225

Product Details anti-TFPI2 Antibody

Target: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFPI2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects TFPI2 (Middle). No cross reactivity with other proteins.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the Middle region of human TFPI2 .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for TFPI2

Target: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Alternative Name: TFPI2 (TFPI2 Products)

Synonyms: MGC68843 antibody, TFPI2 antibody, MGC108301 antibody, si:ch211-262k23.2 antibody, tfpi2 antibody, PP5 antibody, REF1 antibody, TFPI-2 antibody, AV000670 antibody, PP5/TFPI-2 antibody, tissue factor pathway inhibitor 2 L homeolog antibody, tissue factor pathway inhibitor 2 antibody, tfpi2.L antibody, TFPI2 antibody, tfpi2 antibody, Tfpi2 antibody

Background: Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213 amino acids with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex. The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. And there are also high transcript levels in adult mouse liver and kidney.Synonyms: PP5, Placental protein 5, TFPI-2, Tissue factor pathway inhibitor 2

Gene ID: 7980

NCBI Accession: NP_006519

UniProt: P48307