TIMP2 antibody (C-Term)

Catalog No. ABIN1109256

Product Details anti-TIMP2 Antibody

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects TIMP2 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogen: Peptide mapping at the C-terminal end of TIMP-2 of human origin .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 1.2 % sodium acetate or neutral PBS. If 0.5 mL of PBS is used, the antibody concentration will be 100 μg/mL.

Buffer: 50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2 (TIMP2 Products)

Synonyms: CSC-21K antibody, DDC8 antibody, timp2l antibody, zgc:65967 antibody, zgc:85799 antibody, D11Bwg1104e antibody, Timp-2 antibody, TIMP-2 antibody, etID32613.12 antibody, fa96h09 antibody, timp2 antibody, wu:fa96h09 antibody, zgc:136726 antibody, TIMP metallopeptidase inhibitor 2 antibody, TIMP metallopeptidase inhibitor 2b antibody, tissue inhibitor of metalloproteinase 2 antibody, TIMP metallopeptidase inhibitor 2a antibody, TIMP metallopeptidase inhibitor 2 L homeolog antibody, TIMP2 antibody, timp2b antibody, Timp2 antibody, timp2a antibody, timp2.L antibody

Background: TIMP2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition.Synonyms: CSC-21K, Metalloproteinase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2

Gene ID: 7077

NCBI Accession: NP_003246

UniProt: P16035

Pathways: cAMP Metabolic Process