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F4/80 antibody

EMR1 Reactivity: Mouse FACS, IF Host: Rat Monoclonal BM8 unconjugated
Catalog No. ABIN1112492
  • Target See all F4/80 (EMR1) Antibodies
    F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
    Reactivity
    • 84
    • 52
    • 25
    • 3
    • 3
    • 1
    Mouse
    Host
    • 54
    • 45
    • 4
    • 3
    • 2
    • 1
    Rat
    Clonality
    • 53
    • 48
    • 2
    Monoclonal
    Conjugate
    • 40
    • 10
    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This F4/80 antibody is un-conjugated
    Application
    • 77
    • 50
    • 24
    • 17
    • 13
    • 13
    • 12
    • 11
    • 11
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Characteristics
    Rat monoclonal Anti-Mouse F4/80 is recommended for use in flow cytometry for identification of F4/80 glycoprotein, present in macrophages.
    Immunogen
    BALB/c macrophages obtained from 14-day-old bone marrow cell cultures.
    Clone
    BM8
    Isotype
    IgG2a
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    Discover our top product EMR1 Primary Antibody
  • Application Notes
    It is recommended for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of mouse tissue for flow cytometric analysis usingless than or equal to 1 µg/10^6 cells.
    Comment

    Purified, unconjugated.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    The conjugate is provided in liquid form in buffer containing 1% bovine serum albumin (BSA) and 0,09% Sodium azide, pH 7.2.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
    Alternative Name
    F4/80 (EMR1 Products)
    Synonyms
    EMR1 antibody, TM7LN3 antibody, DD7A5-7 antibody, EGF-TM7 antibody, F4/80 antibody, Gpf480 antibody, Ly71 antibody, adhesion G protein-coupled receptor E1 antibody, ADGRE1 antibody, LOC100424335 antibody, Adgre1 antibody
    Background
    F4/80 is a 160 kDa glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8 T cells- mediated peripheral tolerance.
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