Sca-1/Ly-6A/E antibody

Catalog No. ABIN1112503

Product Details anti-Sca-1/Ly-6A/E Antibody

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Sca-1/Ly-6A/E antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Characteristics: Monoclonal Rat Anti-Mouse Ly-6A/E is recommended for use in flow cytometry for identification of the Mouse Ly-6A/E.

Immunogen: IL-2-dependent mouse T-cell line CTL-L

Clone: D7

Isotype: IgG2a

Application Details

Application Notes: It is recommended for use in flow cytometry. This reagent is effective for direct immunofluorescence staining of human tissue for flow cytometric analysis. Recommeded Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometry analysis. For immunofluorescent staining, the suggested use of this reagent is less or equal to 0.1 µg per 10^6 cells in 100 µL volume or 100 µL of whole bloodIt is recommended that the reagent be titrated for optimal performance for each application.

Comment:

Purified, unconjugated.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The conjugate is provided Phosphate-buffered solution, pH 7.2, containing 0.09% Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Sca-1/Ly-6A/E

Target: Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))

Alternative Name: Ly6 A/E (Ly6a Products)

Synonyms: Ly-6A.2 antibody, Ly-6A/E antibody, Ly-6E.1 antibody, Sca-1 antibody, Sca1 antibody, TAP antibody, lymphocyte antigen 6 complex, locus A antibody, Ly6a antibody

Background: Strains expressing the Ly6.1 haplotype have low Ly6A/E expression on resting peripheral lymphocytes. The expression of Ly6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly6A/E is thought to be involved in the regulation of both T and B cell responses.

Pathways: Sensory Perception of Sound, Activated T Cell Proliferation