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LGR5 antibody
LGR5
Reactivity: Mouse
WB, IHC, IHC (p), ICC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-LGR5 Antibody
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Target
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LGR5
(Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
Reactivity
All reactivities for LGR5 antibodies
Mouse
Host
All hosts for LGR5 antibodies
Rabbit
Clonality
All clonalities for LGR5 antibodies
Polyclonal
Conjugate
All conjugates for LGR5 antibodies
This LGR5 antibody is un-conjugated
Application
All applications for LGR5 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
Purification
affinity purified
Isotype
IgG
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Discover our top product LGR5 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB (1:1000-2000), IHC-P (1:200), ICC (1:50). Other applications have not been tested. The optimal dilutions should be determined by end user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Preservative
Sodium azide, Thimerosal (Merthiolate)
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.
Expiry Date
12 months
Target Details for LGR5
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Target
LGR5
(Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
Alternative Name
Leucine-rich repeat-containing G-protein coupled receptor 5, LGR5 (LGR5 Products )
Synonyms
lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
Background
Leucine-rich repeat-containing G-protein coupled receptor 5(LGR5), also known as GPR49, is a 907-amino acid 7-transmembrane protein, belongs to G Protein-Coupled Receptor. The differential expression of GPR49 between normal and tumor tissue was significant. GPR49 was upregulated in colon primary tumor tissues. In addition to colon tumors, GPR49 was also found to be upregulated in ovarian primary tumor tissues. Moreover, the expression level of GPR49 in colon and ovarian tumors increased in more advanced tumors suggesting a role for the receptor in tumor progression.
Pathways
WNT Signaling
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