Caldesmon antibody

Catalog No. ABIN111485

Product Details anti-Caldesmon Antibody

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reactivity: Human, Duck, Avian

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caldesmon antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts with the High Molecular Weight (120-150 kDa) and a Low Molecular Weight (71-80 kDa) forms of Caldesmon, an actin interacting and Calmodulin binding protein found in smooth muscle and other cell types.

Purification: Affinity Chromatography on Protein A

Immunogen: Duck Gizzard Caldesmon (heavy type).

Clone: 12B5

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Caldesmon

Target: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Alternative Name: Caldesmon (CALD1 Products)

Synonyms: CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, NAG22 antibody, l-Cad antibody, 4833423D12Rik antibody, AI195384 antibody, AV071549 antibody, AW536160 antibody, C920027I18Rik antibody, CALD1 antibody, Caldesmon antibody, caldesmon 1 antibody, CALD1 antibody, Cald1 antibody

Background: The caldesmon protein is involved in contraction, cell movement, shape change, exocytosis and endocytosis. It is an actin interacting and calmodulin binding protein found in smooth muscle and other cell types. Caldesmon occurs in both a high molecular weight (120-150 kDa) and a low molecular weight (61-70 kDa) form, depending on the tissue in which it is located. Caldesmon plays a major role in the regulation of smooth muscle and non-muscle contractile events.Synonyms: CAD, CALD1, CDM

Gene ID: 800

NCBI Accession: NP_004333

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction