This antibody recognises the beta subunit of chorionic gonadotrophin (hCG) and shows 0.5 % crossreactivity with the intact hCG molecule. Negligible reactivity has been observed with hLH, hTSH and hFSH.Aff. Const.:2 x 10e10 litres/mole
Purification
Ion exchange chromatography
Immunogen
Chorionic Gonadotropin Beta subunit. Spleen cells from immunised BALB/c mice were fused with cells of the P3X63-Ag 8.653 myeloma cell line.
HCG is a peptide hormone that is composed of one alpha and one beta subunit. hCG shares a common alpha chain with the pituitary hormones FSH, TSH and LH, but has a unique beta chain which is recognised by this antibody. hCG is secreted by placental syncytiotrophoblasts and stimulates the ovaries to produce steroids that are essential to pregnancy.Synonyms: CGB, CGB3, Choriogonadotropin subunit beta, beta hCG, hCG-beta