Collagen Type I antibody

Catalog No. ABIN111744

This anti-Collagen Type I antibody is a Mouse Monoclonal antibody detecting Collagen Type I in IHC (fro) and EIA. Suitable for Human.

Quick Overview for Collagen Type I antibody (ABIN111744)

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Collagen Type I antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: NFI-20

Product Details anti-Collagen Type I Antibody

Specificity: This antibody is specific for Collagen I and does not recognise Collagen types II, III and IV.

Purification: Ammonium Sulphate Precipitation and DEAE-Cellulose Chromatography.

Immunogen: Human Collagen type I.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on Frozen Sections: 1/10-1/40ELISA: 1/500-1/2000. Immunoblotting: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1 mL of sterile distilled water.

Buffer: Contains Mannitol, Dextran and Salts.

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for Collagen Type I

Target: Collagen Type I (COL1) (Collagen, Type I (COL1))

Alternative Name: Collagen Type I

Background: Collagen is located in the extracellular matrix of connective tissues. It is part of the interacting network of proteoglycans and proteins that provides a structural framework for both soft and calcified connective tissues. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis.Synonyms: Alpha-1 type I collagen, Alpha-2 type I collagen, COL1A1, COL1A2

Gene ID: 1277

NCBI Accession: NP_000079

UniProt: P02452