LYZ antibody

Catalog No. ABIN112146

Product Details anti-LYZ Antibody

Target: LYZ (Lysozyme (LYZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LYZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody can be used for the Immunohistochemical detection of histiocytic neoplasia and myeloid leukemias. Monocytic leukemia cells show strong positive immune reaction. Weak reaction is also found with granulocytes. LYZ-Z blocks the catalytic activity of Human Lysozyme.

Cross-Reactivity (Details): Species reactivity (tested):Human. Negative with Rabbit.

Purification: Protein A Chromatography.

Immunogen: Human lysozyme

Clone: LYZ-Z

Isotype: IgG1

Application Details

Application Notes: Immunoblotting. Flow Cytometry. Immunocytology. Immunohistochemistry (1/20): Suitable for Frozen and Paraffin-Embedded Sections. Use PBS with 0.09 % sodium azide and 0.5 % BSA as dilution buffer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in 1.0 mL dist. water.

Buffer: Final solution contains 0.09 % Sodium Azide and 0.5 % BSA in PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) at -20 °C for longer.

Target Details for LYZ

Target: LYZ (Lysozyme (LYZ))

Alternative Name: Lysozyme C (LYZ Products)

Synonyms: LZM antibody, 1 antibody, LYZC antibody, lys-C antibody, zgc:136734 antibody, BmLys antibody, LYS antibody, LZ antibody, LYZS antibody, lysozyme C antibody, LYZ antibody, lysozyme antibody, lysozyme antibody, lysozyme (renal amyloidosis) antibody, lysozyme L homeolog antibody, serum lysozyme antibody, LYZ antibody, lyz antibody, Lzm antibody, LOC781146 antibody, lyz.L antibody, S-LZ antibody

Background: Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears.Synonyms: 1, 4-beta-N-acetylmuramidase C, LYZ, LZM

Gene ID: 4069

NCBI Accession: NP_000230

UniProt: P61626