APOC1 antibody (HRP)

Catalog No. ABIN113011

Product Details anti-APOC1 Antibody (HRP)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOC1 antibody is conjugated to HRP

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Binds to human Apo CI. No cross reactivity with other human plasma apoproteins.

Purification: Immunoaffinitty by Human Apo CI Sepharose column.

Application Details

Application Notes: Can be used for detection of Apo CI in plasma and lipoproteins. Immunoassay and Western blots (dilution 1: 1,000 - 1: 4,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL (prior to lyophilization)

Buffer: 50 mM PBS, pH 7.4 containing 0.1 M Sodium Chloride and 10 mg/mL BSA as stabilizer and 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Alternative Name: Apolipoprotein C I (Apo CI) (APOC1 Products)

Synonyms: Apo-CIB antibody, ApoC-IB antibody, ALPCI antibody, LRRG04 antibody, APOC1 antibody, apoc1 antibody, apolipoprotein C1 antibody, apolipoprotein C-I antibody, Apolipoprotein C-I antibody, APOC1 antibody, Apoc1 antibody, apoc1 antibody

Background: The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Apolipoprotein C-I appears to modulate the interaction of APOE with beta migrating VLDL and inhibit binding of beta VLDL to the LDL receptor related protein.Synonyms: Apo-CI, Ap °C-I, Ap °C1, Apolipoprotein C-I, Apolipoprotein C1

Gene ID: 341

NCBI Accession: NP_001636

UniProt: P02654

Pathways: Apoptosis