Myoglobin antibody

Catalog No. ABIN113128

Product Details anti-Myoglobin Antibody

Target: Myoglobin (MB)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Myoglobin antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), ELISA (Detection)

Specificity: Reacts with cardiac and skeletal forms of myoglobin.

Purification: Affinitty chromatography using immobilized human myoglobin

Purity: > 95 % pure

Immunogen: Highly purified human cardiac myoglobin

Application Details

Application Notes: Immunoassays for human myoglobin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 9.25 mg/mL (OD280nm, E1% = 13)

Buffer: 10 mM sodium phosphate and 0.85 % (w/v) sodium chloride, pH 7.2, containing 0.05 % sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Myoglobin

Target: Myoglobin (MB)

Alternative Name: Myoglobin (MB Products)

Synonyms: PVALB antibody, AI325109 antibody, zgc:65819 antibody, zgc:77764 antibody, MB antibody, DKFZp468H096 antibody, myg antibody, mb antibody, MYF4 antibody, bHLHc3 antibody, myo antibody, Myoglobin antibody, myoglobin antibody, myogenin antibody, MB antibody, Mb antibody, mb antibody, myg antibody, Myog antibody

Background: Myoglobin is a small heme containing protein (153 amino acid residues, molecular weight (w/o heme) 17053 Da and theoretical pI=7.29) responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.Synonyms: MB

Gene ID: 4151

NCBI Accession: NP_005359

UniProt: P02144

Pathways: Brown Fat Cell Differentiation