KIT antibody (C-Term)

Catalog No. ABIN115378

This Rabbit Polyclonal antibody specifically detects KIT in IHC (p). It exhibits reactivity toward Human and Dog.

Quick Overview for KIT antibody (C-Term) (ABIN115378)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KIT Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts with a 145 kDa protein. This antibody can be used in the identification of gastrointestinal stromal tumors.
Cellular Localization: Cell membrane, cytoplasm.

Purification: Purified

Immunogen: A synthetic peptide from c-terminus of Human CD117/c-kit protein.

Application Details

Application Notes: Immunohistochemistry on Paraffin Embedded Sections: Use 1/50-1/100 diluted antibody inan ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: CD117 / C-Kit

Background: C-kits is expressed in many tissues and cells. c-kits is involved in the development of several lineages of stem cells, such as germ cells, neural crest derived melanocytes and hematopoietic precursor cells. This antibody can be used in the identification of gastrointestinal stromal tumors.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR

Gene ID: 3815

NCBI Accession: NP_000213

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity