IL-22 antibody
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- Target See all IL-22 (IL22) Antibodies
- IL-22 (IL22) (Interleukin 22 (IL22))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-22 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- Recognizes Interleukin-22 (IL-22).
- Purification
- Affinity Chromatography employing immobilized Human IL-22 matrix.
- Immunogen
- Highly pure (>98%) E.coli derived recombinant Human Interleukin-22 (hIL-22).
- Top Product
- Discover our top product IL22 Primary Antibody
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- Application Notes
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Neutralization. Sandwich ELISA: To detect Human IL-22 by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with Biotinylated anti-Human IL22 (PP1224B1 orPP1224B2) as detection antibody, allows the detection at least 0.2-0.4 ng/well ofrecombinant Human IL-22. Western blot: To detect Human IL-22 by Western Blot analysis this antibody can be used ata concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant Human IL-22 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS, pH 7.2 without preservatives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Target
- IL-22 (IL22) (Interleukin 22 (IL22))
- Alternative Name
- Interleukin-22 / IL22 (IL22 Products)
- Synonyms
- IL-21 antibody, IL-22 antibody, IL-D110 antibody, IL-TIF antibody, ILTIF antibody, TIFIL-23 antibody, TIFa antibody, zcyto18 antibody, IL-22a antibody, ILTIFa antibody, Iltif antibody, RGD1561292 antibody, interleukin-22 antibody, interleukin 22 antibody, IL22 antibody, il22 antibody, Il22 antibody
- Background
- IL22 is a cytokine structurally related to IL10 and is upregulated in activated T cells. IL22 signals through a receptor complex that includes CRF2-4 and a new member of the class II cytokine receptor family (also known as the interferon receptor family), IL22R. CRF2-4 has previously been demonstrated to be a functional component of the IL-10 signaling complex. IL22 is able to suppress IL4 production, this may have therapeutic potential, particularly in the treatment of asthma.Synonyms: Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF
- Gene ID
- 50616
- NCBI Accession
- NP_065386
- UniProt
- Q9GZX6
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